W4016
蟛蜞菊内酯
≥98% (HPLC), powder
别名:
1,8,9-三羟基-3-甲氧基-6 H -苯并呋喃 [3,2- c ] ] 苯并吡喃-6-酮, 5-甲氧基-5,11,12-三羟基香豆素
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关于此项目
经验公式（希尔记法）:
C16H10O7
化学文摘社编号:
分子量:
314.25
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
产品名称
蟛蜞菊内酯, ≥98% (HPLC), powder
InChI
1S/C16H10O7/c1-21-6-2-10(19)14-12(3-6)23-16(20)13-7-4-8(17)9(18)5-11(7)22-15(13)14/h2-5,17-19H,1H3
SMILES string
COc1cc(O)c-2c(OC(=O)c3c-2oc4cc(O)c(O)cc34)c1
InChI key
XQDCKJKKMFWXGB-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to brown
solubility
DMSO: 10 mg/mL, clear
storage temp.
2-8°C
Quality Level
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相关类别
Biochem/physiol Actions
蟛蜞菊内酯通过阻断 IκBα 的磷酸化和降解抑制细胞内的 NF-κB- 介导的基因转录。IKKα 和 β激酶活性不可逆抑制剂（IC 50 <10βM）。蟛蜞菊内酯对 p38 MAP 激酶或 Akt 没有影响。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 1
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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