WH0004041M1
Monoclonal Anti-LRP5 antibody produced in mouse
clone 1E9, purified immunoglobulin, buffered aqueous solution
别名:
Anti-BMND1, Anti-HBM, Anti-LR3, Anti-LRP7, Anti-OPPG, Anti-OPS, Anti-VBCH2, Anti-low density lipoprotein receptor-related protein 5
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
1E9, monoclonal
Application:
ELISA, WB
Citations:
2
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
1E9, monoclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
ELISA: suitable, western blot: 1-5 μg/mL
isotype
IgG1κ
GenBank accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... LRP5(4041)
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General description
Low-density lipoprotein receptor-related protein 5 or LRP5 functions as a co-receptor for the Wnt signaling complex. LRP5 is involved in various processes such as bone mass regulation, pulmonary angiogenesis, and alveolar synthesis . Monoclonal Anti-LRP5 antibody is specific for LRP5 in humans.
Immunogen
LRP5 (NP_002326.1, 41 a.a. ~ 130 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
RDVRLVDAGGVKLESTIVVSGLEDAAAVDFQFSKGAVYWTDVSEEAIKQTYLNQTGAAVQNVVISGLVSPDGLACDWVGKKLYWTDSETN
Sequence
RDVRLVDAGGVKLESTIVVSGLEDAAAVDFQFSKGAVYWTDVSEEAIKQTYLNQTGAAVQNVVISGLVSPDGLACDWVGKKLYWTDSETN
Physical form
Solution in phosphate buffered saline, pH 7.4
Legal Information
GenBank is a registered trademark of United States Department of Health and Human Services
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
常规特殊物品
此项目有
Tadanori Mammoto et al.
PloS one, 7(7), e41596-e41596 (2012-08-01)
Angiogenesis is crucial for lung development. Although there has been considerable exploration, the mechanism by which lung vascular and alveolar formation is controlled is still not completely understood. Here we show that low-density lipoprotein receptor-related protein 5 (LRP5), a component
Yajun Cui et al.
Nature medicine, 17(6), 684-691 (2011-05-24)
The human skeleton is affected by mutations in low-density lipoprotein receptor-related protein 5 (LRP5). To understand how LRP5 influences bone properties, we generated mice with osteocyte-specific expression of inducible Lrp5 mutations that cause high and low bone mass phenotypes in
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