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WH0004683M1

Monoclonal Anti-NBN antibody produced in mouse

Name: Monoclonal Anti-NBN antibody produced in mouse
Brand: SIGMA

clone 3E4, purified immunoglobulin, buffered aqueous solution

别名:

Anti-ATV, Anti-ATV1, Anti-ATV2, Anti-MGC87362, Anti-NBS, Anti-NBS1, Anti-nibrin

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关于此项目

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD03455620

Conjugate:

unconjugated

Clone:

3E4, monoclonal

Application:

ELISA (i), WB

Citations:

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属性

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

3E4, monoclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

indirect ELISA: suitable, western blot: 1-5 μg/mL

isotype

IgG2aκ

GenBank accession no.

NM_002485

UniProt accession no.

O60934

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... NBN(4683)

说明

General description

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. (provided by RefSeq)

Immunogen

NBN (NP_002476, 645 a.a. ~ 754 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
DDSEMLPKKLLLTEFRSLVIKNSTSRNPSGINDDYGQLKNFKKFKKVTYPGAGKLPHIIGGSDLIAHHARKNTELEEWLRQEMEVQNQHAKEESLADDLFRYNPYLKRRR

Physical form

Solution in phosphate buffered saline, pH 7.4

Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services

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存储类别

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

常规特殊物品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

07096-3E4

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全球贸易项目编号

货号	GTIN
WH0004683M1-100UG	04061829599058