WH0051621M1
Monoclonal Anti-KLF13 antibody produced in mouse
clone 1D3, purified immunoglobulin, buffered aqueous solution
别名:
Anti-BTEB3, Anti-FKLF2, Anti-Kruppel-like factor 13, Anti-NSLP1, Anti-RFLAT1
生物来源
mouse
质量水平
偶联物
unconjugated
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
1D3, monoclonal
表单
buffered aqueous solution
种属反应性
rat, human, mouse
技术
indirect ELISA: suitable
western blot: 1-5 μg/mL
同位素/亚型
IgG2aκ
GenBank登记号
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... KLF13(51621)
一般描述
KLF13 belongs to a family of transcription factors that contain three classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000 [PubMed 11087666]).
RFLAT-1/KLF13 (kruppel like factor 13) belongs to the krüppel-like family of transcription factors. This gene is located on human chromosome 15q13.
免疫原
KLF13 (AAH13946, 31 a.a. ~ 72 a.a) partial recombinant protein.
Sequence
PESRPEGAAVAATPTLPRVEERRDGKDSASLFVVARILADLN
Sequence
PESRPEGAAVAATPTLPRVEERRDGKDSASLFVVARILADLN
应用
Monoclonal Anti-KLF13 antibody has been used in immunoblotting.
生化/生理作用
RFLAT-1/KLF13 (kruppel like factor 13) controls the life cycle of papillomavirus in keratinocytes through STAT5 (signal transducer and activator of transcription 5) and IL-8 (interleukin-8). It participates in cardiac gene transcription and heart development.
外形
Solution in phosphate buffered saline, pH 7.4
法律信息
GenBank is a registered trademark of United States Department of Health and Human Services
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
常规特殊物品
Clinical utility gene card for: 15q13.3 microdeletion syndrome
Tropeano M, et al.
European Journal of Human Genetics, 22(11), 1338-1338 (2014)
KLF13 regulates the differentiation-dependent human papillomavirus life cycle in keratinocytes through STAT5 and IL-8
Zhang W, et al.
Oncogene, 35(42), 5565-5575 (2016)
A carvedilol-responsive microRNA, miR-125b-5p protects the heart from acute myocardial infarction by repressing pro-apoptotic bak1 and klf13 in cardiomyocytes
Bayoumi AS, et al.
Journal of Molecular and Cellular Cardiology, 114, 72-82 (2018)
Ahmed S Bayoumi et al.
Journal of molecular and cellular cardiology, 114, 72-82 (2017-11-11)
Cardiac injury is accompanied by dynamic changes in the expression of microRNAs (miRs), small non-coding RNAs that post-transcriptionally regulate target genes. MiR-125b-5p is downregulated in patients with end-stage dilated and ischemic cardiomyopathy, and has been proposed as a biomarker of
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