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Merck
CN

WH0051621M1

Sigma-Aldrich

Monoclonal Anti-KLF13 antibody produced in mouse

clone 1D3, purified immunoglobulin, buffered aqueous solution

别名:

Anti-BTEB3, Anti-FKLF2, Anti-Kruppel-like factor 13, Anti-NSLP1, Anti-RFLAT1

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关于此项目

UNSPSC代码:
12352203
NACRES:
NA.41
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生物来源

mouse

质量水平

偶联物

unconjugated

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

1D3, monoclonal

表单

buffered aqueous solution

种属反应性

rat, human, mouse

技术

indirect ELISA: suitable
western blot: 1-5 μg/mL

同位素/亚型

IgG2aκ

GenBank登记号

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... KLF13(51621)

一般描述

KLF13 belongs to a family of transcription factors that contain three classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000 [PubMed 11087666]).
RFLAT-1/KLF13 (kruppel like factor 13) belongs to the krüppel-like family of transcription factors. This gene is located on human chromosome 15q13.

免疫原

KLF13 (AAH13946, 31 a.a. ~ 72 a.a) partial recombinant protein.

Sequence
PESRPEGAAVAATPTLPRVEERRDGKDSASLFVVARILADLN

应用

Monoclonal Anti-KLF13 antibody has been used in immunoblotting.

生化/生理作用

RFLAT-1/KLF13 (kruppel like factor 13) controls the life cycle of papillomavirus in keratinocytes through STAT5 (signal transducer and activator of transcription 5) and IL-8 (interleukin-8). It participates in cardiac gene transcription and heart development.

外形

Solution in phosphate buffered saline, pH 7.4

法律信息

GenBank is a registered trademark of United States Department of Health and Human Services

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

常规特殊物品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Clinical utility gene card for: 15q13.3 microdeletion syndrome
Tropeano M, et al.
European Journal of Human Genetics, 22(11), 1338-1338 (2014)
KLF13 regulates the differentiation-dependent human papillomavirus life cycle in keratinocytes through STAT5 and IL-8
Zhang W, et al.
Oncogene, 35(42), 5565-5575 (2016)
A carvedilol-responsive microRNA, miR-125b-5p protects the heart from acute myocardial infarction by repressing pro-apoptotic bak1 and klf13 in cardiomyocytes
Bayoumi AS, et al.
Journal of Molecular and Cellular Cardiology, 114, 72-82 (2018)
Ahmed S Bayoumi et al.
Journal of molecular and cellular cardiology, 114, 72-82 (2017-11-11)
Cardiac injury is accompanied by dynamic changes in the expression of microRNAs (miRs), small non-coding RNAs that post-transcriptionally regulate target genes. MiR-125b-5p is downregulated in patients with end-stage dilated and ischemic cardiomyopathy, and has been proposed as a biomarker of

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