WH0152503M1
Monoclonal Anti-SH3D19 antibody produced in mouse
clone 5C7, purified immunoglobulin, buffered aqueous solution
别名:
Anti-EVE1, Anti-MGC105136, Anti-MGC118910, Anti-SH3 domain protein D19
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关于此项目
NACRES:
NA.43
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
5C7, monoclonal
Application:
ELISA (i), IF, WB
Citations:
3
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
5C7, monoclonal
form
buffered aqueous solution
species reactivity
human, mouse, rat
technique(s)
indirect ELISA: suitable, indirect immunofluorescence: suitable, western blot: 1-5 μg/mL
isotype
IgG3κ
GenBank accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... SH3D19(152503)
General description
SH3 domain containing 19 (SH3D19) is a cytoplasmic protein and the gene encoding it is localized on human chromosome 4q31.3.
Immunogen
SH3D19 (NP_001009555, 94 a.a. ~ 203 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
PVTKPELPKKPNPGLIRSVNPEIPGRGPLAESSDSGKKVPTPAPRPLLLKKSVSSENPTYPSAPLKPVTVPPRLAGASQAKAYKSLGEGPPANPPVPVLQSKPLVDIDLI
Sequence
PVTKPELPKKPNPGLIRSVNPEIPGRGPLAESSDSGKKVPTPAPRPLLLKKSVSSENPTYPSAPLKPVTVPPRLAGASQAKAYKSLGEGPPANPPVPVLQSKPLVDIDLI
Biochem/physiol Actions
SH3 domain containing 19 (SH3D19) inhibits processes induced by Ras oncoprotein. It binds to a protein called EEN (extra eleven-nineteen leukemia fusion gene protein), part of the endophilin family, and modulates the activity of ADAMs (a disintegrin and metalloproteases).
Physical form
Solution in phosphate buffered saline, pH 7.4
Legal Information
GenBank is a registered trademark of United States Department of Health and Human Services
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)