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Merck
CN

X1126

甲苯噻嗪

≥99%, Alpha-2 adrenergic agonist

别名:

2-(2,6-二甲基苯氨基)-5,6-二氢-4H-噻嗪

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关于此项目

经验公式(希尔记法):
C12H16N2S
化学文摘社编号:
分子量:
220.33
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
230-902-1
MDL number:
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产品名称

甲苯噻嗪, ≥99%

InChI key

BPICBUSOMSTKRF-UHFFFAOYSA-N

InChI

1S/C12H16N2S/c1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12/h3,5-6H,4,7-8H2,1-2H3,(H,13,14)

SMILES string

Cc1cccc(C)c1NC2=NCCCS2

assay

≥99%

drug control

Új pszichoaktív anyag / New psychoactive substance (Hungary), 78/2022. (XII. 28.) BM rendelet

storage temp.

−20°C

Quality Level

Application

甲苯噻嗪已用于实验动物的麻醉。

Biochem/physiol Actions

α 2 -肾上腺素受体激动剂、镇静剂、肌肉松弛剂。
与氯胺酮一起使用时,甲苯噻嗪被认为是实验动物中一种强效和安全的麻醉剂。已知其可升高肝脏释放葡萄糖,从而加重高血糖症。

General description

甲苯噻嗪可溶于甲醇 (50 mg/mL),得到澄清、无色溶液。也可溶于稀盐酸和氯仿。甲苯噻嗪几乎不溶于水和碱溶液。

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

法规信息

监管及禁止进口产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Brockman, RP
Research in Veterinary Science, 30(3), 383-384 (1981)
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The pathogenesis of ventilator-induced lung injury has predominantly been attributed to overdistension or mechanical opening and collapse of alveoli, whereas mechanical strain on the airways is rarely taken into consideration. Here, we hypothesized that mechanical ventilation may cause significant airway
Imaging of rat optic nerve axons in vivo
Koch JC, et al.
Nature Protocols, 6(12), 1887-1887 (2011)
Naomi Van Gassen et al.
European journal of immunology, 45(5), 1482-1493 (2015-02-04)
Pancreas injury by partial duct ligation (PDL) activates a healing response, encompassing β-cell neogenesis and proliferation. Macrophages (MΦs) were recently shown to promote β-cell proliferation after PDL, but they remain poorly characterized. We assessed myeloid cell diversity and the factors
Lactobacillus casei addition to a repletion diet-induced early normalisation of cytokine profils during a pneumococcal infection in malnourished mice
Salva S, et al.
Food and agricultural immunology, 19(3), 195-211 (2008)

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