biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous glycerol solution
species reactivity
human, mouse
technique(s)
western blot: 1:1,000 using Jurkat cells treated with H2O2.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... ZAP70(7535)
mouse ... Zap70(22637)
General description
ZAP-70 is a protein tyrosine kinase that is expressed in natural killer cells and T-lymphocytes. ZAP-70 interacts with the ζ chain of the T cell antigen receptor (TCR) and subsequently modulates cell signaling. Phosphorylation of Tyr315 and Tyr319 residues regulates TCR-mediated signal transduction . Anti-phospho-ZAP-70 pTyr315/pTyr319) antibody is specific for human ZAP-70. The product is expected to react with mouse ZAP-70 (as its 100% homologous to human ZAP-70), but has not been tested for it.
Immunogen
synthetic phosphopeptide derived from the region of human ZAP-70 that contains tyrosines 315 and 319.
Application
Anti-phospho-ZAP-70 pTyr315/pTyr319) antibody is suitable for use in western blot (1:1,000 using Jurkat cells treated with H2O2 and immunoblot.
Physical form
Solution in Dulbecco′s phosphate buffered saline (without Mg2+and Ca2+), pH 7.3, with 50% glycerol, 1.0 mg/mL BSA (IgG and protease free) and 0.05% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
怎么回事？
WGK 2
闪点 (F)
Not applicable
闪点 (°C)
Not applicable
PPE（个人防护设备）
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)