Z0502
Zaleplon
≥98% (HPLC), solid
别名:
CL-284846, N-[3-(3-Cyanopyrazolo-[1,5-a]pyrimidin-7-yl)phenyl)-N-ethylacetamide
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关于此项目
经验公式（希尔记法）:
C17H15N5O
化学文摘社编号:
分子量:
305.33
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
assay
≥98% (HPLC)
form
solid
drug control
USDEA Schedule IV; psychotrope (France); regulated under CDSA - not available from Sigma-Aldrich Canada
storage condition
desiccated, protect from light
color
white
solubility
DMSO: ~20 mg/mL, H2O: insoluble
storage temp.
2-8°C
SMILES string
CCN(C(C)=O)c1cccc(c1)-c2ccnc3c(cnn23)C#N
InChI
1S/C17H15N5O/c1-3-21(12(2)23)15-6-4-5-13(9-15)16-7-8-19-17-14(10-18)11-20-22(16)17/h4-9,11H,3H2,1-2H3
InChI key
HUNXMJYCHXQEGX-UHFFFAOYSA-N
Gene Information
human ... GABRA1(2554), GABRB1(2560), GABRG2(2566)
Biochem/physiol Actions
Zaleplon is a non-benzodiazepine agonist at the benzodiazepine site of the GABAA receptor; sedative; hypnotic.
Features and Benefits
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
signalword
Warning
hcodes
Hazard Classifications
Repr. 2 - STOT SE 3
target_organs
Central nervous system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
监管及禁止进口产品
此项目有
Daniela Remane et al.
Analytical and bioanalytical chemistry, 401(4), 1341-1352 (2011-07-21)
For fast and reliable screening, identification, and quantification of as many analytes as possible, multi-analyte approaches are very useful in clinical and forensic toxicology. Using ultra high performance liquid chromatography-tandem mass spectrometry, such an approach has been developed for blood
Monique A J Mets et al.
Sleep medicine reviews, 14(4), 259-267 (2010-02-23)
Disturbed body balance and standing steadiness are problematic for those who wake up at night or in the morning after using hypnotic drugs. As a result, falls and hip fractures are frequently reported in patients using sleep medication. A literature
K W Weitzel et al.
Clinical therapeutics, 22(11), 1254-1267 (2000-12-16)
Insomnia is the subjective complaint of poor sleep or an inadequate amount of sleep that adversely affects daily functioning. For the past 4 decades, treatment of insomnia has shifted away from the use of barbiturates toward the use of hypnotic