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Merck
CN

Z2125

玉米烯酮

fungal mycotoxin

别名:

F-2毒素

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关于此项目

经验公式(希尔记法):
C18H22O5
化学文摘社编号:
分子量:
318.36
UNSPSC Code:
12191503
NACRES:
NA.77
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1350216
Quality level:
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Quality Level

storage temp.

−20°C

SMILES string

C[C@H]1CCCC(=O)CCC\C=C\c2cc(O)cc(O)c2C(=O)O1

InChI

1S/C18H22O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h3,7,10-12,20-21H,2,4-6,8-9H2,1H3/b7-3+/t12-/m0/s1

InChI key

MBMQEIFVQACCCH-QBODLPLBSA-N

Gene Information

mouse ... Esr1(13982)

Biochem/physiol Actions

玉米赤霉烯酮,一种从 镰刀菌中获得的真菌霉菌毒素,可结合雌激素受体(ER)并在新生大鼠中具有向子宫性。它是动物和人类食物谷物中常见的污染物,并且发挥调节/破坏动物和可能人的内分泌功能中雌激素活性。


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pictograms

Health hazardCorrosion

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Repr. 2 - Skin Corr. 1B

存储类别

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

高风险级别生物产品--毒素类产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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H Leffers et al.
Human reproduction (Oxford, England), 16(5), 1037-1045 (2001-05-02)
We have compared the oestrogenic potency of the synthetic oestrogen Zeranol, used as a growth promoter in meat production, and five related compounds, with the potency of 17beta-oestradiol, diethylstilboestrol (DES), genistein, and Bisphenol-A. The potency was assayed by analysing differences
D M Sheehan et al.
Teratology, 29(3), 383-392 (1984-06-01)
Fusarium sp. contaminated feedstuffs elicit adverse estrogenic effects in several commercially important animal species via the mycotoxin zearalenone. An estrogenically active synthetic derivative, zearalanol, is used as an anabolic agent in cattle. Since estrogens can irreversibly alter target tissue development
Katarzyna Cieplińska et al.
Toxins, 11(5) (2019-05-30)
Zearalenone is a frequent contaminant of cereals and their by-products in regions with a temperate climate. This toxic molecule is produced naturally by Fusarium fungi in crops. The aim of this study was to determine the influence of low zearalenone



全球贸易项目编号

货号GTIN
Z2125-25MG04061837617447
Z2125-10MG04061837617430