11023AST
Astec® CHIROBIOTIC® V Chiral (5 μm) HPLC Columns
L × I.D. 15 cm × 4.6 mm, HPLC Column
别名:
Vancomycin Chiral Column
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关于此项目
UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
L × i.d.:
15 cm × 4.6 mm
Particle size:
5 μm
Matrix active group:
vancomycin phase
Pore size:
100 Å
Matrix:
High-purity silica gel particle platform, fully porous particle
产品名称
Astec® CHIROBIOTIC® V 手性 HPLC 色谱柱, 5 μm particle size, L × I.D. 15 cm × 4.6 mm
material
stainless steel column
Quality Level
agency
suitable for USP L88
description
HPLC Column
product line
Astec®
packaging
pkg of 1 ea
manufacturer/tradename
Astec®
parameter
0-45 °C temperature, 80-110 bar pressure (1200-1500 psi)
technique(s)
HPLC: suitable, LC/MS: suitable
L × I.D.
15 cm × 4.6 mm
matrix
High-purity silica gel particle platform, fully porous particle
matrix active group
vancomycin phase
particle size
5 μm
pore size
100 Å
pH range
3.5-7.0
separation technique
chiral
General description
中性分子、酰胺、酸、酯和胺对这些基于万古霉素的CSP具有相当大的对映选择性。在极性离子模式下，在CHIROBIOTIC® V上可分离多种仲胺和叔胺。CHIROBIOTIC® V已被证明具有许多蛋白质固定相的分离特性，但又具有优异的稳定性和更高的样品容量。部分尚无采用其他手性固定相分离报道的手性分析物也已在其上得到分离。CHIROBIOTIC® V和V2的成键化学特性不同，载体颗粒的孔径不同，因而各自具有不同的灵敏度和制备能力。
- 键合相：万古霉素
- 工作pH范围: 3.5 - 7.0
- 粒径：5、10或16 μm
- 孔径：100 Å (CHIROBIOTIC® V)或200 Å (CHIROBIOTIC® V2)
Application
- Development and validation of an UFLC-MS/MS method for enantioselectivity determination of d,l-thero-methylphenidate, d,l-thero-ethylphenidate and d,l-thero-ritalinic acid in rat plasma and its application to pharmacokinetic study.: This study highlights the application of UFLC-MS/MS combined with Astec® CHIROBIOTIC® V Chiral HPLC Column for the enantioselective analysis of various therapeutic agents in rat plasma, providing a crucial methodological advancement for pharmacokinetic research ( Zhang et al., 2016).
Legal Information
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC
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Enantiomeric separation of mirtazapine and its metabolite in rat plasma by reverse polar ionic liquid chromatography using fluorescence and polarimetric detectors connected in series
Rao, R. Nageswara, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 879 (21), 1911-1916 (2011)
Chiral stability-indicating HPLC method for analysis of arotinolol in pharmaceutical formulation and human plasma
Sultan, Maha A., et al.
Arabian Journal of Chemistry, 3 (3), 147-153 (2010)
Hisham Hashem et al.
Journal of chromatography. A, 1218(38), 6727-6731 (2011-08-23)
In this study, a method for enantioseparation of terbutaline and salbutamol was established using Chirobiotic V column as a stationary phase. Polar ionic mode applying mobile phase containing ammonium nitrate in 100% ethanol, pH 5.1 was found to give the
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 11023AST | 04061833513729 |