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Merck
CN

11041-U

Carbopack®吸附剂

matrix Carboxen 1006, 2 μm, bottle of 20 g

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UNSPSC Code:
23201100
EC Number:
231-153-3
NACRES:
SB.52

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product line

Carboxen®

form

powder

packaging

bottle of 20 g

technique(s)

LPLC: suitable

surface area

~715 m2/g

matrix

Carboxen 1006

matrix active group

carbon

particle size

2 μm

pore size

~0.23 cm3/g macroporosity, ~0.26 cm3/g mesoporosity, ~0.29 cm3/g microporosity, ~7-10 Å pore diameter

density

~0.26 g/mL (free fall density)

separation technique

reversed phase

Quality Level

100

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General description

Carboxen是由高分子前体高度改性而成的人造碳吸附剂。这种粒子既不会像树脂一样发生塑性变形，也不会像活性炭一样产生细微颗粒。以干燥形式储运。Carboxen作为衍生树脂适合各种去除小分子和大分子杂质的纯化应用。气相和液相纯化皆可。包括，去除原料药(API)中的均相催化剂，在生化纯化中去除高风险杂质（如，单抗中的残留宿主细胞蛋白），去除重金属，纯化氯化物，去除可萃取物和可浸出物。大小不一的渐变孔径改善了吸附和解吸的热力学和动力学特性。Carboxen形式多样，具有不同的孔结构（微孔、中孔和大孔比例不同）、比表面积和表面pH。
Carboxen® adsorbent is ideally used for solid-phase microextraction (SPME). It is highly efficient in extraction of small polar molecules from aqueous solution.

Application

Carboxen® 1006 was used as an extraction device for the determination of ochratoxins A and B in nuts and grain samples using an automated in-tube solid-phase microextraction (SPME) coupled with liquid chromatography-mass spectrometry (LC-MS).

Features and Benefits

特点及优势：

  • 球形
  • 坚硬，球盘硬度>98%
  • 温度稳定性高达400°C
  • 高纯度
  • 易于填料
  • 全pH范围下稳定
  • 不产生背压
  • 渗透压冲击稳定性高
  • 渐变式孔径（从大孔到中孔再到微孔)

Other Notes

有关更多信息，请访问：特种碳吸附剂

Legal Information

Carboxen is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

11 - Combustible Solids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Applications of Solid Phase Microextraction.
Pawliszyn J.
Science, 64-65 (1999)
Keita Saito et al.
Journal of chromatography. A, 1220, 1-6 (2011-12-20)
A simple and sensitive method for the determination of ochratoxins A and B in nuts and grain samples was developed using an automated in-tube solid-phase microextraction (SPME) coupled with liquid chromatography-mass spectrometry (LC-MS). Ochratoxins were separated within 5 min by
B D Page et al.
Journal of chromatography. A, 873(1), 79-94 (2000-04-11)
The headspace solid-phase microextraction (HS-SPME) efficiencies from vegetable oil of the recently available Carboxen-poly(dimethylsiloxane) (PDMS) and divinylbenzene-Carboxen-PDMS fibres were found to be much greater than those of the PDMS fibre for a number of volatile contaminants. Using these Carboxen-based fibres

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