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12024AST

Astec^® CHIROBIOTIC^® T 手性 HPLC 色谱柱

Name: Astec<SUP>®</SUP> CHIROBIOTIC<SUP>®</SUP> T 手性 HPLC 色谱柱
Brand: SUPELCO

5 μm particle size, L × I.D. 25 cm × 4.6 mm

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eCl@ss:

32110501

NACRES:

SB.52

物料

stainless steel column

Agency

suitable for USP L63

描述

HPLC column

产品线

Astec^®

包装

pkg of 1 ea

manufacturer/tradename

Astec^®

参数

0-45 °C temperature
241 bar pressure (3500 psi)

technique(s)

HPLC: suitable
LC/MS: suitable

长度 × 内径

25 cm × 4.6 mm

基质

High-purity silica gel particle platform
fully porous particle

基质活性基团

teicoplanin glycopeptide phase

粒径

5 μm

孔径

100 Å

operating pH range

3.8-6.8

分离技术

chiral

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一般描述

CHIROBIOTIC^® T和T2具有替考拉宁作为手性选择剂。它们对许多类别的分子可提供独特的选择性，特别是未衍生化的α, β, γ以及环氨基酸、N-衍生氨基酸、羟基-羧基酸，酸性化合物包括羧基酸及酚、小肽、中性芳香族分析物及环状芳香族和脂肪族胺。通常在手性的冠醚或配体交换型CSP上获得的分离也可能发生在CHIROBIOTIC^®T和T2上，但是是在大为简单的移动相如水-乙醇中。此外，所有已知的β-阻滞剂（氨醇）以及二氢香豆素都已被分解。CHIROBIOTIC^® T和T2在它们的键化学和支持颗粒的孔径上存在差别，分别赋予了它们不同的选择和制备能力。

键合相：替考拉宁
操作pH范围：3.8 - 6.8
粒子直径：5、10或16 μm
孔径：100 Å (CHIROBIOTIC^® T)或200 Å (CHIROBIOTIC^® T2)

CHIROBIOTIC FAQ
CHIROBIOTIC 参考书目
Chiral产品文献

法律信息

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany

CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC

应用

产品编号

说明

价格

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

分析证书(COA)

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示例

T1503

货号

25G

包装规格/数量

其它示例：

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

输入内容 1.000309185)

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索取COA

Automated online dual-column extraction coupled with teicoplanin stationary phase for simultaneous determination of (R)- and (S)-propranolol in rat plasma using liquid chromatography-tandem mass spectrometry.

Yuan-Qing Xia et al.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 788(2), 317-329 (2003-04-23)

An automated online sample extraction method for rat plasma was developed and validated for the quantification of (R)- and (S)-propranolol following the intravenous administration of either the racemate or the individual enantiomers at 5 mg/kg. A dual-column extraction system coupled

Effect on separation of injecting samples in a solvent different from the mobile phase.

Knut Gedicke et al.

Journal of chromatography. A, 1162(1), 62-73 (2007-03-03)

The separation of compounds possessing low solubility in the mobile phase could be improved by applying stronger solvents for dissolving the feed. A model system has been investigated with ethanol-water as the mobile phase, Chirobiotic T as the stationary phase

Development and validation of a sensitive LC-MS/MS method for the determination of fenoterol in human plasma and urine samples.

M Sanghvi et al.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 933, 37-43 (2013-07-23)

Due to the lack of sensitivity in current methods for the determination of fenoterol (Fen), a rapid LC-MS/MS method was developed for the determination of (R,R')-Fen and (R,R';S,S')-Fen in plasma and urine. The method was fully validated and was linear

Analysis of the band profiles of the enantiomers of phenylglycine in liquid chromatography on bonded teicoplanin columns using the stochastic theory of chromatography.

P Jander et al.

Journal of chromatography. A, 919(1), 67-77 (2001-07-19)

The retention behaviour of the enantiomers of underivatized phenylglycine was studied on a Chirobiotic T column packed with amphoteric glycopeptide teicoplanin covalently bonded to the surface of silica gel. The retention and the selectivity of separation of the enantiomers increase

Methotrexate determination in pharmaceuticals by enantioselective HPLC.

D Abd el-Hady et al.

Journal of pharmaceutical and biomedical analysis, 37(5), 919-925 (2005-05-03)

A simple, sensitive and selective high performance liquid chromatographic method with UV detection for the chiral separation of racemic methotrexate (rac-Mtx) and enantiomeric purity of L-methotrexate in pharmaceutical formulations was developed and validated. The chiral separation was optimized studying both

查看所有相关文献

Chromatograms

HPLC Analysis of Metaproterenol Enantiomers on Astec^® CHIROBIOTIC^® T

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HPLC Analysis of p-Tyrosine Enantiomers on Astec^® CHIROBIOTIC^® T

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HPLC Analysis of 3,5-Dibromo-p-Tyrosine Enantiomers on Astec^® CHIROBIOTIC^® T

application for HPLC

HPLC Analysis of Propranolol Enantiomers on Astec^® CHIROBIOTIC^® T

application for HPLC展开

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文件

Astec® CHIROBIOTIC® T 手性 HPLC 色谱柱

5 μm particle size, L × I.D. 25 cm × 4.6 mm

属性

物料

Agency

描述

产品线

包装

manufacturer/tradename

参数

technique(s)

长度 × 内径

基质

基质活性基团

粒径

孔径

operating pH range

分离技术

相关类别

说明

一般描述

推荐产品

法律信息

相关产品

应用

相关产品

安全信息

储存分类代码

WGK

闪点(°F)

闪点(°C)

Astec^® CHIROBIOTIC^® T 手性 HPLC 色谱柱