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13019AST

Astec® CHIROBIOTIC® R Chiral (5 μm) HPLC Columns

L × I.D. 15 cm × 2.1 mm, HPLC Column

别名:

CHIROBIOTIC R Chiral Chromatography Column

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关于此项目

UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
L × i.d.:
15 cm × 2.1 mm
Particle size:
5 μm
Matrix active group:
ristocetin A glycopeptide phase
Pore size:
100 Å
Matrix:
high-purity silica gel particle platform, fully porous particle
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产品名称

Astec® CHIROBIOTIC® R手性HPLC柱, 5 μm particle size, L × I.D. 15 cm × 2.1 mm

material

stainless steel column

Quality Level

100

description

HPLC column

product line

Astec®

packaging

pkg of 1 ea

manufacturer/tradename

Astec®

parameter

0-45 °C temperature, 241 bar pressure (3500 psi)

technique(s)

HPLC: suitable, LC/MS: suitable

L × I.D.

15 cm × 2.1 mm

matrix

high-purity silica gel particle platform, fully porous particle

matrix active group

ristocetin A glycopeptide phase

particle size

5 μm

pore size

100 Å

operating pH range

3.5-6.8

separation technique

chiral

General description

CHIROBIOTIC® R色谱柱以高纯硅胶为基质并以共价键键合了瑞斯托菌素A糖肽，已表现出适用于分离阴离子化合物对映体的特殊性能。CHIROBIOTIC ®R的选择性与有机改性剂密切相关，极其有利于醇类流动相。

  • 键合相：瑞斯西丁A
  • pH适用范围：3.5 - 6.8
  • 粒子直径：5、10或16 μm
  • 孔径：100 Å

CHIROBIOTIC FAQ
CHIROBIOTIC参考书目
Chiral产品文献

Application


  • Sensitive determination of D-lactic acid and L-lactic acid in urine by high-performance liquid chromatography-tandem mass spectrometry.: This study demonstrates the application of the Astec CHIROBIOTIC R Chiral HPLC Column in the sensitive determination of D-lactic acid and L-lactic acid in urine samples using HPLC-MS/MS. This highlights its utility in clinical and biomedical research for the analysis of chiral molecules in biological fluids (Henry et al., 2012).

  • New high-performance liquid chromatography method for the determination of (R)-warfarin and (S)-warfarin using chiral separation on a glycopeptide-based stationary phase.: This research utilizes the Astec CHIROBIOTIC R Chiral HPLC Column to develop a method for the chiral separation and determination of warfarin enantiomers. It underscores the column′s application in pharmaceutical analysis, particularly in the study of chiral drug enantiomers (Malakova et al., 2009).



Other Notes

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Legal Information

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC

Still not finding the right product?

Explore all of our products under Astec® CHIROBIOTIC® R手性HPLC柱

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
301455-01
301135-01
300641-01
300640-01
299340-01

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实验方案

Determination of L- and D-Lactic Acid Enantiomers by HPLC/MS/MS

Rapid, simple, reproducible chiral separation and quantification of L- and D-lactic acid enantiomers using Supelco’s Astec CHIROBIOTIC® R chiral column and tandem MS.

Enzyme-catalyzed synthesis of (R)- and (S)-3-hydroxy-3-(10-alkyl-10H-phenothiazin-3-yl)propanoic acids
Brem, Jurgen, et al.
Tetrahedron Asymmetry, 21 (3), 365-373 (2010)
H Henry et al.
Biomedical chromatography : BMC, 26(4), 425-428 (2011-08-16)
D-lactic acid in urine originates mainly from bacterial production in the intestinal tract. Increased D-lactate excretion as observed in patients affected by short bowel syndrome or necrotizing enterocolitis reflects D-lactic overproduction. Therefore, there is a need for a reliable and
B DeCruze et al.
Clinical oncology (Royal College of Radiologists (Great Britain)), 11(4), 252-254 (1999-09-04)
Poor prognosis (poorly differentiated and/or deep myometrial invasion) Stage I endometrial cancer can have a relapse rate as high as 50%. Traditionally, most clinical oncologists treat these patients with external beam radiotherapy after surgery but there is no evidence to
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货号GTIN
13019AST04061833513880