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Merck
CN

13019AST

Astec® CHIROBIOTIC® R Chiral (5 μm) HPLC Columns

L × I.D. 15 cm × 2.1 mm, HPLC Column

别名:

CHIROBIOTIC R Chiral Chromatography Column

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UNSPSC代码:
41115700
eCl@ss:
32110501
NACRES:
SB.52
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产品名称

Astec® CHIROBIOTIC® R手性HPLC柱, 5 μm particle size, L × I.D. 15 cm × 2.1 mm

物料

stainless steel column

质量水平

描述

HPLC column

产品线

Astec®

包装

pkg of 1 ea

制造商/商品名称

Astec®

参数

0-45 °C temperature
241 bar pressure (3500 psi)

技术

HPLC: suitable
LC/MS: suitable

长度 × 内径

15 cm × 2.1 mm

基质

high-purity silica gel particle platform
fully porous particle

基质活性基团

ristocetin A glycopeptide phase

粒径

5 μm

孔径

100 Å

工作pH范围

3.5-6.8

分离技术

chiral

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一般描述

CHIROBIOTIC® R色谱柱以高纯硅胶为基质并以共价键键合了瑞斯托菌素A糖肽,已表现出适用于分离阴离子化合物对映体的特殊性能。CHIROBIOTIC ®R的选择性与有机改性剂密切相关,极其有利于醇类流动相。

  • 键合相:瑞斯西丁A
  • pH适用范围:3.5 - 6.8
  • 粒子直径:5、10或16 μm
  • 孔径:100 Å

CHIROBIOTIC FAQ
CHIROBIOTIC参考书目
Chiral产品文献

应用


  • Sensitive determination of D-lactic acid and L-lactic acid in urine by high-performance liquid chromatography-tandem mass spectrometry.: This study demonstrates the application of the Astec CHIROBIOTIC R Chiral HPLC Column in the sensitive determination of D-lactic acid and L-lactic acid in urine samples using HPLC-MS/MS. This highlights its utility in clinical and biomedical research for the analysis of chiral molecules in biological fluids (Henry et al., 2012).

  • New high-performance liquid chromatography method for the determination of (R)-warfarin and (S)-warfarin using chiral separation on a glycopeptide-based stationary phase.: This research utilizes the Astec CHIROBIOTIC R Chiral HPLC Column to develop a method for the chiral separation and determination of warfarin enantiomers. It underscores the column′s application in pharmaceutical analysis, particularly in the study of chiral drug enantiomers (Malakova et al., 2009).



其他说明

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

法律信息

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Enzyme-catalyzed synthesis of (R)- and (S)-3-hydroxy-3-(10-alkyl-10H-phenothiazin-3-yl)propanoic acids
Brem, Jurgen, et al.
Tetrahedron Asymmetry, 21 (3), 365-373 (2010)
H Henry et al.
Biomedical chromatography : BMC, 26(4), 425-428 (2011-08-16)
D-lactic acid in urine originates mainly from bacterial production in the intestinal tract. Increased D-lactate excretion as observed in patients affected by short bowel syndrome or necrotizing enterocolitis reflects D-lactic overproduction. Therefore, there is a need for a reliable and
P Dehouck et al.
Journal of chromatography. A, 1010(1), 63-74 (2003-09-25)
Erythromycin is a mixture of macrolide antibiotics produced by Saccharopolyspora erythreas during fermentation. A new method for the analysis of erythromycin by liquid chromatography has previously been developed. It makes use of an Astec C18 polymeric column. After validation in
Sébastien Canneaux et al.
The journal of physical chemistry. A, 114(34), 9270-9288 (2010-08-03)
The rate constants of the reactions of iodine atoms with H(2), H(2)O, HI, and OH have been estimated using 39, 21, 13, and 39 different levels of theory, respectively, and have been compared to the available literature values over the
B DeCruze et al.
Clinical oncology (Royal College of Radiologists (Great Britain)), 11(4), 252-254 (1999-09-04)
Poor prognosis (poorly differentiated and/or deep myometrial invasion) Stage I endometrial cancer can have a relapse rate as high as 50%. Traditionally, most clinical oncologists treat these patients with external beam radiotherapy after surgery but there is no evidence to

实验方案

Rapid, simple, reproducible chiral separation and quantification of L- and D-lactic acid enantiomers using Supelco’s Astec CHIROBIOTIC® R chiral column and tandem MS.

Chromatograms

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