14023AST
Astec® CHIROBIOTIC® TAG Chiral (5 μm) HPLC Columns
L × I.D. 15 cm × 4.6 mm, HPLC Column
别名:
Chirobiotic TAG Chiral Chromatography Column
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关于此项目
UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
L × i.d.:
15 cm × 4.6 mm
Particle size:
5 μm
Matrix active group:
teicoplanin aglycone phase
Pore size:
100 Å
Matrix:
High-purity silica gel particle platform, fully porous particle
产品名称
Astec® CHIROBIOTIC® TAG 手性 HPLC色谱 柱, 5 μm particle size, L × I.D. 15 cm × 4.6 mm
material
stainless steel column
Quality Level
agency
suitable for USP L63
description
HPLC column
product line
Astec®
packaging
pkg of 1 ea
manufacturer/tradename
Astec®
parameter
0-45 °C temperature, 241 bar pressure (3500 psi)
technique(s)
HPLC: suitable, LC/MS: suitable
L × I.D.
15 cm × 4.6 mm
matrix
High-purity silica gel particle platform, fully porous particle
matrix active group
teicoplanin aglycone phase
particle size
5 μm
pore size
100 Å
operating pH range
3.0-6.8
separation technique
chiral
General description
去掉三个碳水化合物单体后，CHIROBIOTIC®TAG便有了CHIROBIOTIC®T互补选择性。对于许多氨基酸，α, β, γ环状，尤其是含有硫的蛋氨酸、组氨酸和半胱氨酸的分辨度增高。对于一些中性分子，比如恶唑烷酮、乙内酰脲类和二氮嗪，分辨度也增强了，尤其在单溶剂甲醇、乙醇和乙腈中效果显著。一些酸性分子选择性也增强了
- 连接相：替考拉宁苷元
- pH适用范围：3.0 - 6.8
- 粒子直径：5, 10或16 μm
- 孔径：100 Å
Application
- High-performance liquid chromatographic enantioseparation of 2-aminomono- and dihydroxycyclopentanecarboxylic and 2-aminodihydroxycyclohexanecarboxylic acids on macrocyclic glycopeptide-based phases.: This study emphasizes the effectiveness of the Astec® CHIROBIOTIC® TAG Chiral HPLC Column in the enantioseparation of complex cyclic amino acids. The methodology detailed provides profound insights into the chirality aspects of biochemical molecules, which is crucial for the synthesis of novel pharmaceutical agents and the study of biochemical pathways. This research supports analytical chemists in academia focused on developing chiral analytical methods and advancing chemical synthesis (Berkecz et al., 2009).
Legal Information
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC
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Chemoenzymatic preparation of enantiopure l-benzofuranyl- and l-benzo[b]thiophenyl alanines
Podea, Paula Veronica, et al.
Tetrahedron Asymmetry, 19 (4), 500-511 (2008)
Julia Koidl et al.
Journal of biochemical and biophysical methods, 70(6), 1254-1260 (2007-11-06)
This paper deals with the chiral separation of triiodothyronine (T3) and thyroxine (T4) by HPLC and micro-HPLC. The separation of T3 and T4 is of great pharmaceutical and clinical interest, since the enantiomers exhibit different pharmacological activities. The HPLC measurements
Abdulrahman A Al-Majed
Journal of pharmaceutical and biomedical analysis, 50(1), 96-99 (2009-05-19)
A direct chiral high-performance liquid chromatography (HPLC) method was developed and validated for the resolution and quantification of antiepileptic drug enantiomers, R-(-)- and S-(+)-vigabatrin (gamma-vinyl-gamma-aminobutyric acid) in pharmaceutical products. The separation was optimized on a macrocyclic glycopeptide antibiotic chiral stationary
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 14023AST | 04061833513972 |