15024AST
Astec® CHIROBIOTIC® V2 Chiral (5 μm) HPLC Columns
L × I.D. 25 cm × 4.6 mm, HPLC Column
别名:
Chirobiotic V2 TM=["Astec"]色谱柱
选择尺寸
关于此项目
产品名称
Astec® CHIROBIOTIC® V2手性HPLC色谱柱, 5 μm particle size, L × I.D. 25 cm × 4.6 mm
material
stainless steel column
Quality Level
agency
suitable for USP L88
description
HPLC column
product line
Astec®
packaging
pkg of 1 ea
manufacturer/tradename
Astec®
parameter
0-45 °C temperature, 241 bar pressure (3500 psi)
technique(s)
HPLC: suitable, LC/MS: suitable
L × I.D.
25 cm × 4.6 mm
matrix
High-purity silica gel particle platform, fully porous particle
matrix active group
vancomycin phase
particle size
5 μm
pore size
200 Å
operating pH range
3.5-7.0
separation technique
chiral
General description
- 键合相：万古霉素
- 工作pH范围：3.5 - 7.0
- 粒径：5、10或16 μm
- 孔径：100Å（CHIROBIOTIC® V）或200Å（CHIROBIOTIC® V2）
CHIROBIOTIC FAQ
CHIROBIOTIC参考书目
Chiral产品文献
Application
- Chiral analysis of dextromethorphan and levomethorphan in human hair by liquid chromatography-tandem mass spectrometry： 采用CHIROBIOTIC® V2色谱柱手性分离人体毛发中的右美沙芬和左美沙芬，说明柱子可在法医毒理学中用于准确的手性拆分(Ji et al., 2022)。
- Development and validation of an UFLC-MS/MS method for enantioselectivity determination of d,l-thero-methylphenidate, d,l-thero-ethylphenidate and d,l-thero-ritalinic acid in rat plasma： 在大鼠药动学研究中采用CHIROBIOTIC® V2色谱柱建立对映选择性测定方法，对药物开发和治疗监测有重要意义(Zhang et al., 2016)。
- New high-performance liquid chromatography method for the determination of (R)-warfarin and (S)-warfarin using chiral separation on a glycopeptide-based stationary phase： 用CHIROBIOTIC® V2色谱柱开发新的HPLC方法分离华法林对映体，说明它的临床分析和治疗药物监测用处，体现生物医学研究应用的广泛性(Malakova et al., 2009)。
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实验方案
In this study, optimized methods are presented for sample preparation and chiral chromatography for the LC/MS analysis of amphetamine and methamphetamine enantiomers in urine.
Optimized sample prep and chiral chromatography methods for the LC/MS analysis of these drug enantiomers in urine
Efficient LC-MS separation of methamphetamine enantiomers in urine allows sensitive differentiation of illicit D-methamphetamine from over-the-counter L-methamphetamine.
相关内容
Astec CHIROBIOTIC™ V2 Chiral HPLC Columns offered by Sigma-Aldrich. The polar organic and the polar ionic modes have become increasingly popular largely because of their ideal compatibility with MS detection and preparative LC.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 15024AST | 04061838506986 |