442687
N-亚硝基二乙胺
analytical standard
别名:
二乙基亚硝胺
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关于此项目
线性分子式:
(C2H5)2NNO
化学文摘社编号:
分子量:
102.14
EC Number:
200-226-1
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
1744991
MDL number:
NACRES:
NA.24
产品名称
N-亚硝基二乙胺, analytical standard
InChI key
WBNQDOYYEUMPFS-UHFFFAOYSA-N
InChI
1S/C4H10N2O/c1-3-6(4-2)5-7/h3-4H2,1-2H3
SMILES string
CCN(CC)N=O
grade
analytical standard
CofA
current certificate can be downloaded
packaging
ampule of 1000 mg
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
bp
177 °C (lit.)
density
0.95 g/mL (lit.)
application(s)
cleaning products
cosmetics
environmental
food and beverages
personal care
format
neat
storage temp.
2-30°C
Quality Level
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Application
有关合适仪器技术的更多信息，请参考产品分析证书。如需进一步支持，请联系技术服务。
Other Notes
在我们的NMR在线平台ChemisTwin®上可以找到本品对应的数字化标准物质。您可使用ChemisTwin®上的数字等效品鉴定您的样品并进行定量分析（使用数字化外标）。可查看该物质的NMR谱图，只需点击几次鼠标，就能进行在线样品比对。欢迎点击了解更多，开启免费试用之旅。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Masaaki Miyakoshi et al.
Molecular carcinogenesis, 53(1), 67-76 (2012-08-23)
STAT3 activation is involved in development and progression of hepatocellular carcinoma (HCC). We investigated STAT3 activation during hepatocarcinogenesis induced by neonatal diethylnitrosamine (DEN) treatment in mice. Nuclear accumulation and phosphorylation of STAT3 were detected in altered hepatocyte foci in the
Marta Anna Kowalik et al.
Oncotarget, 6(36), 38749-38763 (2015-10-10)
Although the expression of the stem/progenitor cell marker cytokeratin-19 (CK-19) has been associated with the worst clinical prognosis among all HCC subclasses, it is yet unknown whether its presence in HCC is the result of clonal expansion of hepatic progenitor
Takeki Uehara et al.
Toxicological sciences : an official journal of the Society of Toxicology, 132(1), 53-63 (2013-01-05)
Hepatocellular carcinoma (HCC) mostly develops in patients with advanced fibrosis; however, the mechanisms of interaction between a genotoxic insult and fibrogenesis are not well understood. This study tested a hypothesis that fibrosis promotes HCC via a mechanism that involves activation
L Verna et al.
Pharmacology & therapeutics, 71(1-2), 57-81 (1996-01-01)
N-Nitrosodiethylamine (NDEA) is DNA reactive after bioactivation and produces tumors in every animal species tested. Bioactivation is effected by several P450 isozymes including CYP2E1, which is ethanol inducible. Tumor formation in rat liver was proportional to O4-ethyldeoxythymidine formation in DNA
Michael T Dill et al.
Hepatology (Baltimore, Md.), 57(4), 1607-1619 (2012-11-24)
Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCC) are the most common liver tumors and a leading cause for cancer-related death in men. Notch2 regulates cellular differentiation in the developing and adult liver. Although aberrant Notch signaling is implicated in various cancers
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