产品名称
LiChrospher® RP-18 HPLC 色谱柱, 5 μm particle size, L × I.D. 25 cm × 4 mm
material
stainless steel column
agency
suitable for USP L1
product line
LiChrospher®
feature
endcapped: no
manufacturer/tradename
LiChrospher®
packaging
1 ea of
extent of labeling
21% Carbon loading
parameter
≤70 °C temp. range
400 bar pressure (5801 psi)
technique(s)
HPLC: suitable
L × I.D.
25 cm × 4 mm
surface area
350 m2/g
matrix
octadecyl
silica particle platform
fully porous particle
matrix active group
C18 (octadecyl) phase
particle size
5 μm
pore size
100 Å
operating pH
2-7.5
application(s)
food and beverages
separation technique
reversed phase
Quality Level
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Application
- HPLC-UV and GC-MS Methods for Determination of Chlorambucil and Valproic Acid in Plasma for Further Exploring a New Combined Therapy of Chronic Lymphocytic Leukemia.: This study developed and validated HPLC-UV and GC-MS methods for determining chlorambucil and valproic acid in plasma, aiming to explore their combined therapy for chronic lymphocytic leukemia. The LiChrospher® RP-18 HPLC Column was instrumental in achieving the separation and quantification (Lipska et al., 2021).
- Rapid Determination of Metronidazole and 2-Hydroxymetronidazole in Murine Blood Plasma.: This research utilized the LiChrospher® RP-18 HPLC Column for the rapid determination of metronidazole and its metabolite in murine blood plasma, highlighting its effectiveness in pharmacokinetic studies (Zemanová et al., 2022).
- Application of chemometric approach for development and validation of high performance liquid chromatography method for estimation of ropinirole hydrochloride.: This paper presents a chemometric approach to developing and validating an HPLC method for estimating ropinirole hydrochloride, utilizing the LiChrospher® RP-18 column for precise and accurate results (Fatima et al., 2019).
- A New Solid-Phase Extraction Method for Determination of Pantoprazole in Human Plasma Using High-Performance Liquid Chromatography.: The study developed a novel solid-phase extraction method for determining pantoprazole in human plasma using HPLC with the LiChrospher® RP-18 column, achieving high sensitivity and specificity (Zendelovska et al., 2019).
- Application of an HPLC-MS/MS method for Teicoplanin drug substance and related impurities, part 2: Identity assignment of related impurities.: This research employed the LiChrospher® RP-18 column in an HPLC-MS/MS method to identify and assign related impurities in teicoplanin drug substances, demonstrating the column′s capability in impurity profiling (Tengattini et al., 2019).
General description
LiChrospher® RP-18 HPLC column (L × I.D. 25 cm × 4 mm) is found to be reliable and high versatile. Suitable for reversed-phase high performance liquid chromatography (RP-HPLC) of acidic, neutral and weakly basic compounds, according to L1 USP specifications.
Legal Information
LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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