产品名称
Supelclean™ LC-18 固相萃取管, bed wt. 100 mg, volume 1 mL, pk of 108
material
PE frit (20 μm porosity)
polypropylene hardware
product line
Supelclean™
feature
endcapped
composition
bed wt., 100 mg
packaging
pk of 108
extent of labeling
~11.5% C loading
technique(s)
solid phase extraction (SPE): suitable
surface area
475 m2/g
volume
1 mL
matrix
silica gel base material (irregularly shaped)
matrix active group
C18 (octadecyl) bonding, monomerically bonded
particle size
45 μm
pore size
0.8 cm3/g pore volume
60 Å pore size
Quality Level
application(s)
food and beverages
separation technique
reversed phase
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Application
Supelclean™ LC-18 SPE Tube may be used for the solid-phase extraction of:
- Artesunate, dihydroartemisinin, mefloquine, amodiaquine and desethylamodiaquine in human plasma samples prior to their determination by reversed phase high performance liquid chromatography (RP-HPLC) coupled to electrochemical (EC) detector or ultraviolet (UV) detector.
- Ursodeoxycholic acid in blood serum samples prior to its analysis by HPLC-UV.
- Calycosin-7-O-β-D-glucoside, ononin, astragaloside IV, astragaloside I and ferulic acid in rat plasma samples after oral administration of Danggui Buxue Tang extract, prior to their pharmacokinetic studies by LC coupled to mass spectrometry (MS).
General description
Supelclean™ LC-18 SPE tube is used in solid phase extraction (SPE) method to extract non-polar to moderately polar compounds from aqueous samples.
Legal Information
Supelclean is a trademark of Sigma-Aldrich Co. LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Validation of high performance liquid chromatography-electrochemical detection methods with simultaneous extraction procedure for the determination of artesunate, dihydroartemisinin, amodiaquine and desethylamodiaquine in human plasma for application in clinical pharmacological studies of artesunate-amodiaquine drug combination.
Lai CS, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 877(5-6), 558-562 (2009)
Simultaneous determination of calycosin-7-O-β-D-glucoside, ononin, astragaloside IV, astragaloside I and ferulic acid in rat plasma after oral administration of Danggui Buxue Tang extract for their pharmacokinetic studies by liquid chromatography-mass spectrometry.
Wen XD, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 865(1-2), 99-105 (2008)
An analytical method with a single extraction procedure and two separate high performance liquid chromatographic systems for the determination of artesunate, dihydroartemisinin and mefloquine in human plasma for application in clinical pharmacological studies of the drug combination.
Lai CS, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 857(2), 308-314 (2007)
Barbara Sivakova et al.
International journal of molecular sciences, 22(4) (2021-02-13)
The phosphorylation of proteins modulates various functions of proteins and plays an important role in the regulation of cell signaling. In recent years, label-free quantitative (LFQ) phosphoproteomics has become a powerful tool to analyze the phosphorylation of proteins within complex
M Nobilis et al.
Journal of pharmaceutical and biomedical analysis, 24(5-6), 937-946 (2001-03-15)
Ursodeoxycholic acid (3 alpha,7 beta-dihydroxy-5 beta-cholanoic acid, UDCA) is a therapeutically applicable bile acid widely used for the dissolution of cholesterol-rich gallstones and in the treatment of chronic liver diseases associated with cholestasis. UDCA is more hydrophilic and less toxic
商品
Reversed-phase interaction will retain most molecules with hydrophobic character; it is very useful for extracting analytes that are very diverse in structure within the same sample.
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