Merck
CN

504955

Supelco

Discovery® C18 高效液相色谱柱

5 μm particle size, L × I.D. 15 cm × 4.6 mm

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eCl@ss:
32110501

Agency

suitable for USP L1

质量水平

特点

endcapped

manufacturer/tradename

Discovery®

标记范围

12% Carbon loading

参数

≤70 °C temp. range
400 bar pressure (5801 psi)

technique(s)

HPLC: suitable

长度 × 内径

15 cm × 4.6 mm

表面积

300 m2/g

表面覆盖度

3 μmol/m2

杂质

<10 ppm metals

基质

silica gel, high purity, spherical particle platform

基质活性基团

C18 (octadecyl) phase

粒径

5 μm

孔径

180 Å

operating pH range

2-8

application(s)

food and beverages

分离技术

reversed phase

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一般描述

Discovery® C18 可用于针对 C18 的任何方法。该色谱柱具有对称的峰形、优良的重现性和稳定性等特点,适用于所有常规和高要求的 C18 方法,是此类方法的理想选择。

特点和优势

  • 优良的重现性
  • 分析酸性和碱性化合物均可获得良好的峰形
  • 稳定性好、低流失,适用于 LC-MS 分析
  • 能够分离多肽和小分子蛋白质
  • 与很多同类 C18 色谱柱相比,疏水性更小,因此分析速度更快

推荐产品

探索最适于 HPLCLC-MS 分析的 LiChropur 试剂

法律信息

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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T Nagano et al.
Journal of dental research, 88(9), 823-828 (2009-09-22)
Mmp-20 and Klk4 are the two key enamel proteases. Can both enzymes process amelogenin to generate the major cleavage products that accumulate during the secretory stage of amelogenesis? We isolated Mmp-20 and Klk4 from developing pig teeth and used them
Yuan-Qing Xia et al.
Rapid communications in mass spectrometry : RCM, 20(12), 1831-1837 (2006-05-18)
A major challenge in selecting an appropriate stationary phase for diastereomeric separation is that it is difficult to predict which of the commercially available stationary phases could achieve the required liquid chromatographic (LC) separation. This work describes the selection and
T R Shantha Kumar et al.
Journal of pharmaceutical and biomedical analysis, 38(1), 173-179 (2005-05-24)
A simple, precise and accurate isocratic reverse-phase liquid chromatography method with programmed wavelength detection has been validated to quantify DRF-4367 and Phenol red, simultaneously for application in rat in situ single pass intestinal perfusion study to assess intestinal permeability of
Satoru Sonoke et al.
Cancer research, 68(21), 8843-8851 (2008-11-01)
The pharmacokinetics and antitumor activity of pegylated small interfering RNA (siRNA)/cationic liposome complexes were studied after systemic administration to mice. We designed pegylated-lipid carriers for achieving increased plasma concentrations of RNA and hence improved accumulation of RNA in tumors by
R Nageswara Rao et al.
Biomedical chromatography : BMC, 23(11), 1145-1150 (2009-05-16)
A highly sensitive and selective on-line two-dimensional reversed-phase liquid chromatography/electrospray ionization-tandem mass spectrometry (2D-LC-ESI/MS/MS) method was developed and validated to determine rifaximin in rat serum by direct injection. The 2D-LC-ESI/MS/MS system consisted of a restricted access media column for trapping

实验方案

Studies have suggested that there is a correlation between furosemide and improved racing performance, prompting the horse racing industry to monitor the use of this drug

Separations of Tetracycline Antibiotics by Reversed Phase HPLC, Using Discovery Columns

相关内容

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Chromatograms

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