51099AST
Astec® Cellulose DMP Chiral (5 μm) HPLC Column
L × I.D. 25 cm × 4.6 mm, HPLC Column
别名:
纤维素DMP手性固定相
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关于此项目
UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
L × i.d.:
25 cm × 4.6 mm
Particle size:
5 μm
Matrix active group:
cellulose, DMPC- phase
Pore size:
100 Å pore size
Matrix:
fully porous particle, silica gel high purity, spherical, silica gel particle platform
产品名称
Astec ® 纤维素 DMP 手性 HPLC 色谱柱, 5 μm particle size, L × I.D. 25 cm × 4.6 mm
material
stainless steel column
agency
suitable for USP L40
product line
Astec®
packaging
pkg of 1 ea
manufacturer/tradename
Astec®
parameter
0-40 °C temperature, 50 bar pressure (725 psi)
technique(s)
HPLC: suitable
L × I.D.
25 cm × 4.6 mm
matrix
fully porous particle, silica gel high purity, spherical, silica gel particle platform
matrix active group
cellulose, DMPC- phase
particle size
5 μm
pore size
100 Å pore size
operating pH
3.5-6.8
separation technique
chiral
Quality Level
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Application
- 尿液和血浆中具有叔胺结构的合成卡西酮对映异构体的分离。：本研究探讨了Astec纤维素DMP手性HPLC色谱柱在生物样品中合成卡西酮对映异构体分离中的应用。研究表明，该色谱柱在分离对映异构体方面具有较高的分离度和灵敏度，特别是在尿液和血浆等复杂基质中。这突出了该色谱柱在法医和临床分析中的实用性，为生物样品中手性药物的检测和定量提供了可靠方法（Meetani et al., 2019）。
General description
Astec®纤维素 DMP HPLC 色谱柱在正相、极性有机和 SFC 条件下分离多种手性化合物。它们具有高效率、高负载能力和极好的色谱柱使用寿命。Astec®纤维素DMP具有与其他DMPC衍生的纤维素CSP相当的性能，但价格却低得多，是每个手性色谱柱HPLC或SFC筛选方案的必备必备成分。Astec ® 纤维素 DMP 与其他 Astec ® CSP 互补，包括 CHIROBIOTIC ®、CYCLOBOND 和 P-CAP ™ 产品线。
描述：球形多孔二氧化硅，涂有DMPC（氨基甲酸二甲基苯酯）衍生的纤维素
颗粒直径：5μm
使用范围： 正相、极性有机和 SFC 模式下的小分子对映异构体分离
描述：球形多孔二氧化硅，涂有DMPC（氨基甲酸二甲基苯酯）衍生的纤维素
颗粒直径：5μm
使用范围： 正相、极性有机和 SFC 模式下的小分子对映异构体分离
Legal Information
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC
P-CAP is a trademark of Sigma-Aldrich Co. LLC
Katrijn De Klerck et al.
Journal of pharmaceutical and biomedical analysis, 69, 77-92 (2012-03-01)
Chirality has a significant impact on drug discovery and development processes in the pharmaceutical industry. As the number of enantiopure drugs launched onto the market is yearly increasing, the need for fast and performant enantioseparation methods with minimal costs is
Katrijn De Klerck et al.
Journal of chromatography. A, 1328, 85-97 (2014-01-21)
Since their introduction on the market the applicability of immobilized polysaccharide-based chiral stationary phases in high-performance liquid chromatography has been thoroughly investigated. These immobilized phases have the benefit to be applicable with a wide range of modifiers, potentially extending the
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