产品名称
BIOshell™ IgG 1000 Å C18, 2.7 μm HPLC Column, column L × I.D. 15 cm × 500 μm
material
stainless steel hardware
agency
suitable for USP L1
feature
endcapped
packaging
pkg of 1 unit
extent of labeling
1.4% Carbon loading
technique(s)
HPLC: suitable
column L × I.D.
15 cm × 500 μm
surface area
22 m2/g
matrix
Fused-Core® particle platform
matrix active group
C18 (diisobutyloctadecylsilane) bonding phase
particle size
2.7 μm
pore size
1000 Å pore size
operating pH range
1-8
separation technique
reversed phase
Quality Level
product line
BIOshell™
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Analysis Note
The target analytes include monoclonal antibodies, antibody-drug conjugates, antibody fragments and large proteins with molecular weights up to 500 kDa.
Legal Information
Fused-Core is a registered trademark of Advanced Materials Technology, Inc.
BIOshell is a trademark of Sigma-Aldrich Co. LLC
Application
General description
BIOshell™ IgG 1000 Å C18 is a high-speed, high-performance liquid chromatography column based on a new wide-pore (1000 Å) Fused-Core® particle design. The particle provides a thin porous shell of high-purity silica surrounding a solid silica core. This particle design exhibits very high column efficiency due to the shallow diffusion paths in the 0.5 μm thin porous shell and the small overall particle size of 2.7 μm. The sterically protected C18 bonded phase of BIOshell™ IgG 1000 Å C18 provides a stable, reversed-phase packing that can be used for separating high molecular weight compounds, such as proteins.
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