产品名称
SUPELCOSIL™ LC-8 HPLC 柱, 5 μm particle size, L × I.D. 15 cm × 4.6 mm
物料
stainless steel column
质量水平
Agency
suitable for USP L7
产品线
SUPELCOSIL™
特点
endcapped
包装
1 ea of
标记范围
6.0% carbon loading
参数
≤70 °C temp. range
技术
HPLC: suitable
长度 × 内径
15 cm × 4.6 mm
表面积
170 m2/g
表面覆盖度
surface coverage 3.2 μmol/m2
基质
silica gel, spherical particle platform
fully porous particle
基质活性基团
C8 (octyl) phase
粒径
5 μm
孔径
120 Å
pH值范围
2-7.5
应用
food and beverages
分离技术
reversed phase
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一般描述
比 C18 疏水性更小的相。对于极性和非极性化合物，保留性都比 C18 更小。将含低于 5% 有机溶剂修正的流动相用于 C8 柱上，而不是 C18 柱上。极性化合物在 C8 柱上比在 C18 柱上的保留性相对更强。
应用
- Chromatographic behaviour of ionic liquid cations in view of quantitative structure-retention relationship.: This study explores the chromatographic behavior of ionic liquid cations using quantitative structure-retention relationships (QSRR). The SUPELCOSIL™ LC-8 HPLC Column was utilized to analyze retention data for various ionic liquids, providing insights into their separation mechanisms and potential applications in analytical chemistry (Molíková et al., 2010).
- Liquid chromatographic method for the determination of lidocaine and monoethylglycine xylidide in human serum containing various concentrations of bilirubin for the assessment of liver function.: The research presents a liquid chromatographic method using the SUPELCOSIL™ LC-8 HPLC Column to determine lidocaine and its metabolite in human serum. This method is particularly useful for assessing liver function by measuring drug metabolism (Piwowarska et al., 2004).
- LC determination of morphine and morphine glucuronides in human plasma by coulometric and UV detection.: The research describes a method for the determination of morphine and its glucuronides in human plasma. Utilizing the SUPELCOSIL™ LC-8 HPLC Column, the study demonstrates the method′s sensitivity and applicability in pharmaceutical analysis (Ary et al., 2001).
法律信息
SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
F Belal et al.
Journal of pharmaceutical and biomedical analysis, 24(3), 335-342 (2001-02-24)
A simple, rapid and sensitive HPLC method has been developed for the simultaneous determination of ramipril and hydrochlorothiazide in their dosage forms. Acetonitrile: sodium perchlorate solution (0.1 M) adjusted to pH 2.5+/-0.2 with phosphoric acid (46:54 v/v), was used as
Thomas Borch et al.
Journal of chromatography. A, 1022(1-2), 83-94 (2004-02-03)
Explosives such as 2,4,6-trinitrotoluene (TNT), octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX), and hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) are widely distributed environmental contaminants. Complete chromatographic separation is necessary in order to accurately determine and quantify explosives and their degradation products in environmental samples and in (bio)transformation studies. The
Vesna Cerkvenik-Flajs et al.
Analytica chimica acta, 663(2), 165-171 (2010-03-09)
An analytical method has been developed for the simultaneous determination of the following endectocide drugs in milk: ivermectin, abamectin, doramectin, moxidectin, eprinomectin, emamectin and nemadectin. Samples were extracted with acetonitrile, purified with solid-phase extraction on a reversed phase C(8), derivatised
L Dal Bo et al.
Journal of chromatography. B, Biomedical applications, 665(2), 404-409 (1995-03-24)
A simple HPLC method has been developed for the determination of ticlopidine in human plasma. Plasma samples were buffered at pH 9 and extracted with n-heptane-isoamyl alcohol (98.5:1.5, v/v). Imipramine was used as internal standard. Chromatography was performed isocratically with
J H Nichols et al.
Clinical chemistry, 40(7 Pt 1), 1312-1316 (1994-07-01)
This automated assay determines the concentration of the antidepressant fluoxetine (Prozac) and its active metabolite norfluoxetine in serum by reversed-phase HPLC with spectrophotometric detection. Extraction, injection, and quantification are performed by the Gilson Aspec automated sample handler. The patient's specimen
Chromatograms
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