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Supelco

SUPELCOSIL™ LC-8 HPLC 柱

5 μm particle size, L × I.D. 25 cm × 4.6 mm

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eCl@ss:
32110501

Agency

suitable for USP L7

质量水平

100

特点

endcapped

制造商/商品名称

SUPELCOSIL™

标记范围

6.0% carbon loading

参数

≤70 °C temp. range
400 bar pressure (5801 psi)

技术

HPLC: suitable

长度 × 内径

25 cm × 4.6 mm

表面积

170 m2/g

表面覆盖度

surface coverage 3.2 μmol/m2

基质

silica gel, spherical particle platform

基质活性基团

C8 (octyl) phase

粒径

5 μm

孔径

120 Å

pH值范围

2-7.5

应用

food and beverages

分离技术

reversed phase

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相关类别

一般描述

比 C18 疏水性更小的相。对于极性和非极性化合物，保留性都比 C18 更小。将含低于 5% 有机溶剂修正的流动相用于 C8 柱上，而不是 C18 柱上。极性化合物在 C8 柱上比在 C18 柱上的保留性相对更强。

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法律信息

SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC

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705578-5MG-PW

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F Belal et al.
Journal of pharmaceutical and biomedical analysis, 24(3), 335-342 (2001-02-24)
A simple, rapid and sensitive HPLC method has been developed for the simultaneous determination of ramipril and hydrochlorothiazide in their dosage forms. Acetonitrile: sodium perchlorate solution (0.1 M) adjusted to pH 2.5+/-0.2 with phosphoric acid (46:54 v/v), was used as
Jadwiga Piwowarska et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 805(1), 1-5 (2004-04-29)
A high-performance liquid chromatographic method is described for determination of lidocaine (2-(dietyloamino)-N-(2,6-dimetylofenylo) acetamid) and its metabolite, monoethylglycine xylidide (MEGX), in human serum containing various concentration of bilirubin. Lidocaine and its metabolite were extracted from human serum using dichloromethane. After separation
K Ary et al.
Journal of pharmaceutical and biomedical analysis, 26(2), 179-187 (2001-07-27)
A reversed-phase high-performance liquid chromatographic method with coulometric and UV detection has been developed for the simultaneous determination of morphine, morphine-3-glucuronide and morphine-6-glucuronide. The separation was carried out by using a Supelcosil LC-8 DB reversed-phase column and 0.1 M potassium
P K Kunicki
Journal of chromatography. B, Biomedical sciences and applications, 750(1), 41-49 (2001-02-24)
A HPLC-UV determination of clobazam and N-desmethylclobazam in human serum and urine is presented. After simple liquid-liquid extraction with dichloromethane the compounds and an internal standard diazepam were separated on a Supelcosil LC-8-DB column at ambient temperature under isocratic conditions
Thomas Borch et al.
Journal of chromatography. A, 1022(1-2), 83-94 (2004-02-03)
Explosives such as 2,4,6-trinitrotoluene (TNT), octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX), and hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) are widely distributed environmental contaminants. Complete chromatographic separation is necessary in order to accurately determine and quantify explosives and their degradation products in environmental samples and in (bio)transformation studies. The
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