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Merck
CN

59353-U21

Discovery® C8 (5 µm) HPLC Columns

L × I.D. 15 cm × 2.1 mm, HPLC Column

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UNSPSC代码:
41115700
eCl@ss:
32110501
NACRES:
SB.52
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产品名称

Discovery ® C8 HPLC 色谱柱, 5 μm particle size, L × I.D. 15 cm × 2.1 mm

物料

stainless steel column

质量水平

Agency

suitable for USP L7

产品线

Discovery®

特点

endcapped

制造商/商品名称

Discovery®

包装

1 ea of

标记范围

7.5% Carbon loading

参数

≤70 °C temp. range
400 bar pressure (5801 psi)

技术

HPLC: suitable
LC/MS: suitable

长度 × 内径

15 cm × 2.1 mm

表面积

200 m2/g

表面覆盖度

3.4 μmol/m2

杂质

<10 ppm metals

基质

silica gel, high purity, spherical base material
fully porous particle

基质活性基团

C8 (octyl) phase

粒径

5 μm

孔径

180 Å

工作pH范围

2-8

应用

food and beverages

分离技术

reversed phase

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特点和优势

  • 优良的重现性。
  • 分析强疏水性化合物时比 C18 柱快
  • 稳定性好、低流失,适用于 LC-MS 分析
  • 分析碱性和酸性化合物均可获得良好峰形
  • 可兼容低有机溶剂/高含水量的流动相

法律信息

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

法规信息

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分析证书(COA)

Lot/Batch Number

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Scott C Bell et al.
Pharmacology & therapeutics, 145, 19-34 (2014-06-17)
With the discovery of the CFTR gene in 1989, the search for therapies to improve the basic defects of cystic fibrosis (CF) commenced. Pharmacological manipulation provides the opportunity to enhance CF transmembrane conductance regulator (CFTR) protein synthesis and/or function. CFTR
Bo-Rui Kang et al.
Bioorganic & medicinal chemistry letters, 25(24), 5808-5812 (2015-11-08)
2-Benzylisoquinolin-1(2H)-ones has been proposed as vasodilative agents on the basis of scaffold hopping. In the present study, a series of 2-benzylisoquinolin-1(2H)-ones were synthesized. Their vasodilative effects were evaluated by wire myograph on isolated rat mesenteric arterial ring induced contraction with
H Jayasuriya et al.
Journal of natural products, 55(5), 696-698 (1992-05-01)
Bioassay-directed fractionation of a Chinese medicinal plant, Polygonum cuspidatum (Polygonaceae), has led to the discovery of an anthraquinone, emodin [1], as a strong inhibitor of a protein tyrosine kinase (p56lck) partially purified from bovine thymus. Comparison of the IC50 values
J Reniers et al.
European journal of medicinal chemistry, 46(12), 6104-6111 (2011-10-25)
Previous studies on 5H-indeno[1,2-c]pyridazin-5-one derivatives as inhibitors of MAO-B revealed that it was possible to increase the MAO-B inhibitory potency of 5H-indeno[1,2-c]pyridazin-5-ones by substituting the central heterocycle in the 3-position or C-8 with lipophilic groups which occupy the substrate cavity
Laurence Conraux et al.
PloS one, 8(11), e79733-e79733 (2013-11-14)
The diagnostic of Amyotrophic lateral sclerosis (ALS) remains based on clinical and neurophysiological observations. The actual delay between the onset of the symptoms and diagnosis is about 1 year, preventing early inclusion of patients into clinical trials and early care

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