59354-U
Discovery® C8 (5 µm) HPLC Columns
L × I.D. 25 cm × 4.6 mm, HPLC Column
别名:
C8反相色谱柱
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关于此项目
UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
L × i.d.:
25 cm × 4.6 mm
Particle size:
5 μm
Matrix active group:
C8 (octyl) phase
Pore size:
180 Å
Matrix:
silica gel, high purity, spherical base material
fully porous particle
fully porous particle
产品名称
Discovery ® C8 HPLC 色谱柱, 5 μm particle size, L × I.D. 25 cm × 4.6 mm
material
stainless steel column
agency
suitable for USP L7
product line
Discovery®
feature
endcapped
manufacturer/tradename
Discovery®
packaging
1 ea of
extent of labeling
7.5% Carbon loading
parameter
≤70 °C temp. range
400 bar pressure (5801 psi)
technique(s)
HPLC: suitable
LC/MS: suitable
L × I.D.
25 cm × 4.6 mm
surface area
200 m2/g
surface coverage
3.4 μmol/m2
impurities
<10 ppm metals
matrix
silica gel, high purity, spherical base material
fully porous particle
matrix active group
C8 (octyl) phase
particle size
5 μm
pore size
180 Å
operating pH range
2-8
application(s)
food and beverages
separation technique
reversed phase
Quality Level
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Application
Discovery® C8 HPLC 色谱柱可用于通过固相微萃取（SPME）和之后的高效液相色谱-串联质谱（HPLC-MS / MS）联用法测定包括尿液、培养物和组织在内的生物基质中的双酚A、染料木黄酮、双酚A β-D-葡萄糖醛酸 (BPA gluc) 和染料木黄酮4′-β-D-葡萄糖醛酸 (genistein gluc)。
Features and Benefits
- 优良的重现性。
- 分析强疏水性化合物时比 C18 柱快
- 稳定性好、低流失，适用于 LC-MS 分析
- 分析碱性和酸性化合物均可获得良好峰形
- 可兼容低有机溶剂/高含水量的流动相
Legal Information
Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany
Measurement of bisphenol A, bisphenol A β-d-glucuronide, genistein, and genistein 4′- β-d-glucuronide via SPE and HPLC-MS/MS.
Coughlin LJ, et al.
Analytical and Bioanalytical Chemistry, 401, 995-1002 (2011)
Laurence Conraux et al.
PloS one, 8(11), e79733-e79733 (2013-11-14)
The diagnostic of Amyotrophic lateral sclerosis (ALS) remains based on clinical and neurophysiological observations. The actual delay between the onset of the symptoms and diagnosis is about 1 year, preventing early inclusion of patients into clinical trials and early care
Rahul Palchaudhuri et al.
Cell reports, 13(9), 2027-2036 (2015-12-15)
Apoptosis is generally believed to be a process that requires several hours, in contrast to non-programmed forms of cell death that can occur in minutes. Our findings challenge the time-consuming nature of apoptosis as we describe the discovery and characterization
Scott C Bell et al.
Pharmacology & therapeutics, 145, 19-34 (2014-06-17)
With the discovery of the CFTR gene in 1989, the search for therapies to improve the basic defects of cystic fibrosis (CF) commenced. Pharmacological manipulation provides the opportunity to enhance CF transmembrane conductance regulator (CFTR) protein synthesis and/or function. CFTR
M Q Zhang et al.
Die Pharmazie, 46(10), 687-700 (1991-10-01)
The rapid growth in the quinolone research changed the whole face of the previous SAR concepts. So far structural modifications at all positions of the quinolone nucleus except the 4-oxo group have successfully lead to the discovery of potent antimicrobial
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