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Merck
CN

59680-U

Supel™ BioSPME 96-Pin Device

pack of 1 ea

别名:

Supel™ BioSPME 96-Pin Device

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NACRES:
NB.21
UNSPSC Code:
41104018

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产品名称

Supel™ BioSPME 96-Pin Device, pack of 1 ea

packaging

pack of 1 ea

technique(s)

solid phase microextraction (SPME): suitable

matrix active group

C18 coating

application(s)

clinical
pharmaceutical

compatibility

for use with automated robotic liquid handling systems

Quality Level

100

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相关类别

Analysis Note

small molecules having molecular weights up to 1 kDa and logP range from 1-5

General description

The Supel™ BioSPME 96-Pin Device combines BioSPME technology with high throughput free fraction determination for plasma protein binding studies and other free analyte analyses commonly performed by pharma and clinical laboratories. This fast, micro-sample prep device comprises a 96-pin universal format that fits into the wells of standard 96-well plates. The pins are coated with C18 particles and a patented binder that allows for small analytes of interest to bind, while larger macromolecules cannot. This extraction technique is shown to be more than three times faster than rapid equilibrium dialysis methods with improved data quality. Supel™ BioSPME 96-Pin Device workflow can be performed on automation robots via handling with standard gripper paddles, or alternatively can be achieved using a manual technique.

Legal Information

Supel is a trademark of Sigma-Aldrich Co. LLC

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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分析证书(COA)

Lot/Batch Number

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商品

BioSPME for Plasma Protein Binding Assay: Details of Method Development and Optimization

Determination of plasma protein binding using a SupelTM C18 pin device based BioSPME method for efficient sample preparation, along with a comparison to the equilibrium dialysis method.

Protein Binding Determination - Comparison Study of Techniques & Devices

Comparative analysis of Supel™ BioSPME 96-Pin device with a rapid equilibrium dialysis technique for accuracy of measured values, sample cleanliness, and workflow time in drug protein binding.

Speed, Simplicity and Accuracy of Protein Binding Determination using BioSPME

Learn about Supel™ BioSPME C18 high-throughput devices to determine plasma protein binding and decrease the sample preparation time to less than an hour.

Sample Cleanliness Using BioSPME

Learn about Supel™ BioSPME C18 96-pin tool to prepare a clean sample with minimal matrix effects for an LC-MS/MS analysis from human plasma and its comparison with acetonitrile-based precipitation.

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相关内容

Supel™ BioSPME 96-Pin Devices

Supel™ BioSPME 96-Pin devices enhance speed and simplicity for plasma protein binding studies and LCMS analyses.

Supel™ BioSPME 96头固相微萃取装置

相对于快速平衡透析技术，Supel™ BioSPME 96头固相微萃取装置可提高血浆蛋白结合研究及其他游离分析物分析的速度和简便性，同时确保准确、可重现的LCMS结果。

User Guide - 59683-U, 59680-U

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