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Merck
CN

822859

TSKgel® UltraSW Aggregate (3 µm) HPLC Columns

L x I.D. 4 cm × 6 mm, diol phase

别名:

TSKgel® Size Exclusion (SW-Type) HPLC Guard Column

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UNSPSC Code:
41115711
NACRES:
NB.21
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产品名称

TSKgel® UltraSW Aggregate Guard Column, phase diol, L × I.D. 4 cm × 6 mm, 3 μm particle size

material

stainless steel

agency

suitable for USP L20
suitable for USP L59

product line

TSKgel®

manufacturer/tradename

Tosoh UltraSW Aggregate Guard Column

parameter

≤0.5 M salt concentration
0-100% aqueous soluble organic solvents
1 mL/min flow rate
10-30 °C temperature

technique(s)

HPLC: suitable

L × I.D.

4 cm × 6 mm

matrix

silica particle platform

matrix active group

diol phase

particle size

3 μm

pore size

300 Å

operating pH

2.5-7.5

separation technique

size exclusion (SEC)

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General description

The TSKgel SuperSW and UltraSW mAb columns consist of three specialized columns designed for the separation and analysis of monoclonal antibodies (mAb). While mAbs can be analyzed using many different modes of HPLC, size exclusion is best for aggregation, dimer, and fragmentation, making it the best method for heterogeneity studies.

TSKgel UltraSW Aggregate columns have a slightly larger pore size and smaller (3 μm) particle size than the industry-leading TSKgel G3000SWxl (5 μm) and SuperSW3000 (4 μm) columns. These 30 cm x 7.8 mm ID silica-based, stainless steel columns offer reduced lot-to-lot variation, long column life, reduction of unspecified adsorption, and superior recovery of aggregates.

The calibration curve of the TSKgel UltraSW Aggregrate column shows a separation range up to around 2 million Da, which provides better resolution of aggregates/multimers of a mAb than the TSKgel SuperSW mAb columns..

Other Notes

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Physical form

Shipped in 0.05% NaN3 and 0.1 M Na2SO4 in 0.1 M phosphate buffer, pH 6.7.

Legal Information

TSKgel is a registered trademark of Tosoh Corporation

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