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This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ. Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate. Download your certificate at: http://www.sigma-aldrich.com.

Ametoctradin is a fungicide that belongs to the class of triazolo-pyrimidylamines in FRAC group 45. Ametoctradin is a mitochondrial respiration inhibitor that binds to the complex III (complex bc₁) in the electron transport chain of oomycete pathogens, causing a rapid decrease in oxygen consumption and intracellular ATP levels. It is effective in controlling late blight and downy mildews in potato, grape, cucumber, apple, tomato, and other crops.

Ametoctradin has to be monitored in the Multiannual Control Programmes for Pesticides Residues (MACP), run within the EU and EFTA in/on products of plant origin.
Ametoctradin is approved for its use in the EU under Reg. (EC) No 1107/2009. Maximum residue levels (MRLs) have been set according to Reg (EC) No 2021/1110 for ametoctradin for various products of plant and animal origin from 0.01 to 60 mg/kg.

It is intended to be used as a certified reference material (CRM) for calibration in chromatography and other analytical techniques.
Ametoctradin CRM may also find its use as described below:

• QuEChERS method to analyze ametoctradin residue in apple, cucumber, cabbage, tomato, and grape using UPLC-MS/MS.
• Comparative study of three sample preparation methods for multi-residue extraction of pesticide residues analysis in hop matrix.
• Simultaneous and rapid analysis of 300 pesticide residues in human hair using LC-MS/MS and GC-MS/MS.
• To determine the behavior of field-applied pesticides in barley during the malting and mashing stages of beermaking.
• To study the effect of new generation fungicides on Saccharomyces cerevisiae growth, grape must fermentation, and aroma biosynthesis.

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany