CRM38703
鱼藤酮
certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
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关于此项目
经验公式（希尔记法）:
C23H22O6
化学文摘社编号:
分子量:
394.42
NACRES:
NA.24
UNSPSC Code:
41116107
Beilstein/REAXYS Number:
6773081
MDL number:
SMILES string
COc1cc2OCC3Oc4c5C[C@@H](Oc5ccc4C(=O)C3c2cc1OC)C(C)=C
InChI
1S/C23H22O6/c1-11(2)16-8-14-15(28-16)6-5-12-22(24)21-13-7-18(25-3)19(26-4)9-17(13)27-10-20(21)29-23(12)14/h5-7,9,16,20-21H,1,8,10H2,2-4H3/t16-,20-,21+/m1/s1
InChI key
JUVIOZPCNVVQFO-HBGVWJBISA-N
grade
certified reference material, TraceCERT®
product line
TraceCERT®
shelf life
limited shelf life, expiry date on the label
manufacturer/tradename
Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
bp
210-220 °C/0.5 mmHg (lit.)
mp
159-164 °C (lit.)
storage temp.
2-8°C
Quality Level
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General description
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com
Biochem/physiol Actions
线粒体电子转运抑制剂。
鱼藤酮是烟酰胺腺嘌呤二核苷酸（NADH）：泛醌氧化还原酶线粒体电子传递的一种抑制剂。它能够很容易的通过节肢动物的外骨骼被吸收，但皮肤或哺乳动物的胃肠道的吸收则不佳。鱼藤酮作为一种神经毒素能产生帕金森样症状，从而作为一种动物模型用于作为病因和干预措施的研究。鱼藤酮的主要作用机制是通过抑制线粒体复合物Ⅰ造成氧化应激和氧化损伤。由于鱼藤酮的亲脂性，它可以渗入大脑，结合并抑制线粒体电子传递链(ETC)中的复合物Ⅰ。
Legal Information
TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
Hazard Classifications
Acute Tox. 1 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
法规信息
农药列管产品
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