material
PTFE-faced butyl septum, aluminum seal (with 10 mm center hole)
hardness
50 (Durometer: shore A)
packaging
pkg of 100 ea
O.D.
20 mm
diam. × thickness
20 mm × 3.0 mm
fitting
thread for 20 mm
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General description
Product image shown is PTFE faced butyl septum; crimp seal not shown.
Application
Crimp seal with PTFE/butyl septum (Pharma-Fix) may be used to seal standard residual solvents for the determination of residual solvents in drug substances using headspace gas-chromatography coupled with flame ionization detector (HS-GC-FID).
PTFE-faced butyl septum was used in sealing headspace vials to analyse the sampling efficiency and breakthrough of methyl bromide on activated charcoal using GC. It was also used for sealing water samples during headspace analysis with GC-FID, in a study which demonstrates cross-validation of methods used for methyl-tert-butyl ether (MTBE) analysis.
Measuring residual solvents in pharmaceutical samples using fast gas chromatography techniques.
Rocheleau J-M, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 805(1), 77-86 (2004)
Cross-validation of methods used for analysis of MTBE and other gasoline components in groundwater.
Lacorte, S., et al.
Chromatographia, 56, 739-744 (2002)
Sampling and stability of methyl bromide on activated charcoal.
Gan, Jianying, et al.
Journal of Agricultural and Food Chemistry, 43, 1361-1367 (1995)
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