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Merck
CN

1012065

USP

阿昔洛韦

United States Pharmacopeia (USP) Reference Standard

别名:

9-[(2-羟基乙氧基)甲基]鸟嘌呤, 阿苷洛韦

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关于此项目

经验公式(希尔记法):
C8H11N5O3
化学文摘社编号:
分子量:
225.20
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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产品名称

阿昔洛韦, United States Pharmacopeia (USP) Reference Standard

InChI key

MKUXAQIIEYXACX-UHFFFAOYSA-N

SMILES string

NC1=Nc2c(ncn2COCCO)C(=O)N1

InChI

1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15)

grade

pharmaceutical primary standard

API family

acyclovir

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

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Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Acyclovir USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Acyclovir Capsules
  • Acyclovir for Injection
  • Acyclovir Injection
  • Acyclovir Ointment
  • Acyclovir Oral Suspension
  • Acyclovir Tablets

General description

Acyclovir is a nucleoside analogue antiviral drug. It is a highly potent inhibitor of herpes simplex virus. It is related to cytarabine, idoxuridine, trifluridine and vidarabine.

Other Notes

Sales restrictions may apply.

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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D M Richards et al.
Drugs, 26(5), 378-438 (1983-11-01)
Acyclovir (aciclovir) is a nucleoside analogue antiviral drug related to cytarabine, idoxuridine, trifluridine and vidarabine. In common with these earlier antivirals, acyclovir is active against some members of the herpesvirus group of DNA viruses. The efficacy of topical acyclovir has
G B Elion
The American journal of medicine, 73(1A), 7-13 (1982-07-20)
Acyclovir, an acrylic purine nucleoside analog, is a highly potent inhibitor of herpes simplex virus (HSV), types 1 and 2, and varicella zoster virus, and has extremely low toxicity for the normal host cells. This selectivity is due to the
Derivative spectrophotometric method for determination of acyclovir in polymeric nanoparticles.
Tavares, Guilherme Diniz, et al.
Quimica nova, 35.1, 203-206 (2012)
Ahlem Ben Sassi et al.
The Indian journal of medical research, 127(2), 183-192 (2008-04-12)
Tunisian Chrysanthemum species are known to have medicinal activity and some of the species are used in traditional medicine. We have earlier shown the use of C. trifurcatum flowerheads in Tunisian traditional medicine to treat constipation. In the present study
Suneel Chilukuri et al.
Dermatologic clinics, 21(2), 311-320 (2003-05-22)
In immunocompetent patients, HSV is controlled rapidly by the human host's immune system, and recurrent lesions are small and short lived. When treated with antiviral agents, these patients rarely develop resistance to these drugs. In contrast immunocompromised patients might not

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