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Merck
CN

1075757

USP

比索洛尔 半富马酸盐

United States Pharmacopeia (USP) Reference Standard

别名:

1- [4-[[2-(1-甲基乙氧基)乙氧基]甲基]苯氧基] -3-[(1-甲基乙基)氨基] -2-丙醇 半富马酸盐

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关于此项目

经验公式(希尔记法):
C18H31NO4 · .5C4H4O4
化学文摘社编号:
分子量:
383.48
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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InChI

1S/2C18H31NO4.C4H4O4/c2*1-14(2)19-11-17(20)13-23-18-7-5-16(6-8-18)12-21-9-10-22-15(3)4;5-3(6)1-2-4(7)8/h2*5-8,14-15,17,19-20H,9-13H2,1-4H3;1-2H,(H,5,6)(H,7,8)/b;;2-1+

SMILES string

OC(=O)\C=C\C(O)=O.CC(C)NCC(O)COc1ccc(COCCOC(C)C)cc1.CC(C)NCC(O)COc2ccc(COCCOC(C)C)cc2

InChI key

VMDFASMUILANOL-WXXKFALUSA-N

grade

pharmaceutical primary standard

API family

bisoprolol

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

Gene Information

human ... ADRB1(153)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Biochem/physiol Actions

心脏选择性 β1-肾上腺素受体拮抗剂。

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Repr. 2 - STOT RE 2

target_organs

Heart

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

监管及禁止进口产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Bisoprolol Fumarate and Hydrochlorothiazide Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 45(2) (2013)
Bisoprolol Fumarate Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 44(5) (2013)
Naseem A Charoo et al.
Journal of pharmaceutical sciences, 103(2), 378-391 (2014-01-03)
Literature data relevant to the decision to allow a waiver of in vivo bioequivalence (BE) testing for the approval of immediate-release (IR) solid oral dosage forms containing bisoprolol as the sole active pharmaceutical ingredient (API) are reviewed. Bisoprolol is classified
Roman Gähwiler et al.
Praxis, 103(9), 527-531 (2014-04-24)
We report the case of a 38-year patient who presented in our outpatient clinic for cardiac evaluation and assessment as volunteer firefighter. The patient had an asymptomatic sinustachycardia, which was diagnosed at the age of 15. After we excluded secondary
Does β selectivity really affect outcome?
Jordan Field Wicker et al.
Anesthesiology, 120(5), 1286-1287 (2014-04-24)

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