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1091006

USP

硫酸卡普霉素

Name: 硫酸卡普霉素
Brand: USP

United States Pharmacopeia (USP) Reference Standard

别名:

Capreomycin sulfate salt

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关于此项目

化学文摘社编号:

1405-37-4

MDL number:

MFCD00079032

UNSPSC Code:

41116107

NACRES:

NA.24

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属性

grade

pharmaceutical primary standard

API family

capreomycin

form

solid

manufacturer/tradename

USP

application(s)

USP Biologics
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[S](=O)(=O)(O)O.N1CCC(N=C1N)C2NC(=O)\C(=C\NC(=O)N)\NC(=O)C(NC(=O)C(NC(=O)C(CNC2=O)N)CO)CNC(=O)CC(N)CCCN

InChI

1S/C25H44N14O8.H2O4S/c26-4-1-2-11(27)6-17(41)32-8-14-20(43)35-15(9-34-25(30)47)21(44)39-18(13-3-5-31-24(29)38-13)23(46)33-7-12(28)19(42)37-16(10-40)22(45)36-14;1-5(2,3)4/h9,11-14,16,18,40H,1-8,10,26-28H2,(H,32,41)(H,33,46)(H,35,43)(H,36,45)(H,37,42)(H,39,44)(H3,29,31,38)(H3,30,34,47);(H2,1,2,3,4)/b15-9-;

InChI key

AJQVUIHGEOLMDY-SOCRLDLMSA-N

说明

General description

Capreomycin sulfate is a cyclic polypeptide antibiotic produced by Streptomyces capreolus. It is used as a second-line treatment for multidrug-resistant tuberculosis (MDR-TB) and exhibits bacteriostatic activity by inhibiting protein synthesis through ribosomal binding. The USP reference standard supports microbiological assay methods and identity confirmation by chromatographic and spectroscopic techniques.

The USP biologics antibiotics category includes a wide range of antimicrobial agents that are essential in treating bacterial infections. These antibiotics are derived from various natural sources or synthesized to combat specific pathogens effectively. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of antibiotic therapeutics throughout their lifecycle.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Application

Capreomycin sulfate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

Capreomycin for Injection
Capreomycin Sulfate

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

This product is part of the USP Biologics program.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

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pictograms

GHS08,GHS07

signalword

Danger

hcodes

H302 + H312 + H332,H360

pcodes

P202 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Repr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c