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Merck
CN

1478403

USP

奥洛他定 盐酸盐

United States Pharmacopeia (USP) Reference Standard

别名:

(11Z)-11- [3-(二甲氨基)亚丙基]-6,11-二氢二苯并 [b,e] 氧杂萘-2-乙酸 盐酸盐, AL-4943A, KW-4679, 奥洛他定, 帕坦诺

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关于此项目

经验公式(希尔记法):
C21H23NO3·HCl
化学文摘社编号:
分子量:
373.87
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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grade

pharmaceutical primary standard

agency

USP

API family

olopatadine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

Cl.CN(C)CC\C=C1\c2ccccc2COc3ccc(CC(O)=O)cc13

InChI

1S/C21H23NO3.ClH/c1-22(2)11-5-8-18-17-7-4-3-6-16(17)14-25-20-10-9-15(12-19(18)20)13-21(23)24;/h3-4,6-10,12H,5,11,13-14H2,1-2H3,(H,23,24);1H/b18-8-;

InChI key

HVRLZEKDTUEKQH-NOILCQHBSA-N

Gene Information

human ... HRH1(3269)

General description

Find answers to frequently asked questions on USP products in USP FAQs.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Olopatadine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Olopatadine Hydrochloride Ophthalmic Solution

Biochem/physiol Actions

奥洛他定是一种双效组胺 H1 受体拮抗剂和肥大细胞稳定剂。
奥洛他定是一种组胺 H1 受体拮抗剂和肥大细胞稳定剂。大脑中的 H1 受体占位级别较低解释了奥洛他定镇静作用较低的原因。一般认为奥洛他定是 P-糖蛋白的底物,限制了其脑渗透。

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.


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pictograms

Skull and crossbonesEnvironment

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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