V900343
L-精氨酸
≥98%, Vetec™
别名:
(S)-2-氨基-5-胍基戊酸
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关于此项目
线性分子式:
H2NC(=NH)NH(CH2)3CH(NH2)CO2H
化学文摘社编号:
分子量:
174.20
Beilstein:
1725413
EC 号:
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
产品名称
L-精氨酸, Vetec™, reagent grade, ≥98%
等级
reagent grade
产品线
Vetec™
方案
≥98%
表单
powder
颜色
white
mp
222 °C (dec.) (lit.)
SMILES字符串
N[C@@H](CCCNC(N)=N)C(O)=O
InChI
1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m0/s1
InChI key
ODKSFYDXXFIFQN-BYPYZUCNSA-N
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应用
- L-Arginine-Dependent Nitric Oxide Production in the Blood of Patients with Type 2 Diabetes: A Pilot, Five-Year Prospective Study.：本文研究L-精氨酸对糖尿病患者一氧化氮生成的影响，体现它治疗糖尿病血管并发症的用处(Stoian et al., 2024)。
生化/生理作用
一氧化氮合成酶的底物，可转化为瓜氨酸和一氧化氮 (NO)。通过与一氧化氮相关的机理诱导胰岛素释放。
法律信息
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
13 - Non Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Palaniraja Thandapani et al.
Molecular cell, 50(5), 613-623 (2013-06-12)
Motifs rich in arginines and glycines were recognized several decades ago to play functional roles and were termed glycine-arginine-rich (GAR) domains and/or RGG boxes. We review here the evolving functions of the RGG box along with several sequence variations that
Ahmed Moursy et al.
Nucleic acids research, 42(10), 6659-6672 (2014-04-03)
Regulation of SMN2 exon 7 splicing is crucial for the production of active SMN protein and the survival of Spinal Muscular Atrophy (SMA) patients. One of the most efficient activators of exon 7 inclusion is hnRNP G, which is recruited
Jia-Yi Dong et al.
American heart journal, 162(6), 959-965 (2011-12-06)
Previous studies suggest that L-arginine, an amino acid and a substrate of nitric oxide synthase, may have blood pressure (BP)-lowering effect. Because some studies were performed with limited number of patients with hypertension and therefore limited statistical power with sometimes
Diane N Singhroy et al.
Retrovirology, 10, 73-73 (2013-07-23)
Protein arginine methyltransferase 6 (PRMT6) is a nuclear enzyme that methylates arginine residues on histones and transcription factors. In addition, PRMT6 inhibits HIV-1 replication in cell culture by directly methylating and interfering with the functions of several HIV-1 proteins, i.e.
Vivianne J Goosens et al.
Biochimica et biophysica acta, 1843(8), 1698-1706 (2013-10-22)
The twin-arginine protein translocation (Tat) system has a unique ability to translocate folded and co-factor-containing proteins across lipid bilayers. The Tat pathway is present in bacteria, archaea and in the thylakoid membranes of chloroplasts and, depending on the organism and
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