V900437
胸腺嘧啶
Vetec™, reagent grade, 99%
别名:
2,4-二羟基-5-甲基嘧啶, 5-甲基尿嘧啶
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关于此项目
经验公式（希尔记法）:
C5H6N2O2
化学文摘社编号:
分子量:
126.11
EC Number:
200-616-1
UNSPSC Code:
41106305
PubChem Substance ID:
Beilstein/REAXYS Number:
117880
MDL number:
产品名称
胸腺嘧啶, Vetec™, reagent grade, 99%
InChI key
RWQNBRDOKXIBIV-UHFFFAOYSA-N
InChI
1S/C5H6N2O2/c1-3-2-6-5(9)7-4(3)8/h2H,1H3,(H2,6,7,8,9)
SMILES string
CC1=CNC(=O)NC1=O
grade
reagent grade
product line
Vetec™
assay
99%
mp
~320 °C (dec.) (lit.)
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Legal Information
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Lakshminarayan M Iyer et al.
Nucleic acids research, 41(16), 7635-7655 (2013-07-03)
Discovery of the TET/JBP family of dioxygenases that modify bases in DNA has sparked considerable interest in novel DNA base modifications and their biological roles. Using sensitive sequence and structure analyses combined with contextual information from comparative genomics, we computationally
Cai Shen et al.
Chemical communications (Cambridge, England), 49(5), 508-510 (2012-12-04)
Supramolecular patterns formed by adsorption from a liquid of nucleobase-terminated molecular rods on a graphite surface were investigated by scanning tunneling microscopy.
M Weinfeld et al.
Progress in nucleic acid research and molecular biology, 68, 139-149 (2001-09-14)
The toxic and mutagenic effects of ionizing radiation are believed to be caused by damage to cellular DNA. We have made use of a novel immunoassay for thymine glycol to examine the removal of this lesion from the DNA of
Paulina Prorok et al.
PloS one, 7(12), e51776-e51776 (2012-12-20)
Oxygen free radicals induce lipid peroxidation (LPO) that damages and breaks polyunsaturated fatty acids in cell membranes. LPO-derived aldehydes and hydroxyalkenals react with DNA leading to the formation of etheno(ε)-bases including 1,N(6)-ethenoadenine (εA) and 3,N(4)-ethenocytosine (εC). The εA and εC
Ibtissam Talhaoui et al.
Nucleic acids research, 41(2), 912-923 (2012-12-05)
Hydroxyl radicals predominantly react with the C(8) of purines forming 7,8-dihydro-8-oxoguanine (8oxoG) and 7,8-dihydro-8-oxoadenine (8oxoA) adducts, which are highly mutagenic in mammalian cells. The majority of oxidized DNA bases are removed by DNA glycosylases in the base excision repair pathway.
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