See the Full Metabolic Syndrome Picture By Multiplexing Metabolic Biomarkers
Metabolic syndrome involves a combination of serious health issues such as diabetes and obesity. Multiplex immunoassays are critical in this research because they provide a full picture of the different conditions related to metabolic syndrome as well as save the researcher valuable time and sample volume.
What is Metabolic Syndrome?
Metabolic syndrome is a state of low-grade inflammation that contributes to a combination of conditions that impact metabolism and hormones. Obesity, diabetes, and associated conditions, under the umbrella of metabolic syndrome, are urgent health issues. Key features of the metabolic syndrome include:
- Insulin resistance
- Glucose intolerance
- Hypertension
- Dyslipidemia
- Central obesity
- Neuropathy
These symptoms are risk factors for atherosclerosis, coronary heart disease, type 2 diabetes, kidney disease, and even premature death. Adults with metabolic syndrome show inflammation, which may be linked to metabolism via dysregulated adipocyte production of pro- and anti-inflammatory factors.
Biomarkers for Metabolic Syndrome
Biomarkers for metabolic syndrome include cytokines, acute phase proteins, diabetes, and obesity-related hormones, as well as endocrine biomarkers. The expanding portfolio of MILLIPLEX® multiplex metabolic assays helps detect endocrine biomarkers, hormones, insulin-like growth factors, and binding proteins, myokines, bone metabolism biomarkers, and more, to advance your metabolic syndrome research.
Multiplexing Metabolic Syndrome Biomarkers
Multiplexing metabolic syndrome biomarkers allow researchers to gain a complete picture of the various conditions associated with metabolic syndrome. The following graphs in Figure 1 show data for selected analytes of human plasma/serum samples assayed using the MILLIPLEX® Human Metabolic Hormone Panel V3.
Figure 1. Two groups of non-diabetic control serum/plasma, fasted (n=14) and post-fasted (n=14), were sourced commercially and run according to protocol in the Human Metabolic Hormone Panel V3 (Cat. No. HMH3-34K).
Metabolic and Gut Hormones
Gut hormones regulate gut motility and secretion, pancreatic islet hormone secretion, food intake, and energy expenditure.
For Research Use Only. Not For Use In Diagnostic Procedures.
If you cannot find the assay you are looking for, we also offer custom assay services to help you multiplex it your way and develop the right assay for your research.
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