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HomeCalibration, Qualification & ValidationTitripac® Sustainable Packaging for Ready-to-Use Certipur® pH Buffers

Titripac® Sustainable Packaging for Ready-to-Use Certipur® pH Buffers

Shailly Krishna Rajusth, Ingrid Hayenga, Product Managers Reference Materials

Merck

Article from Analytix Reporter - Issue 13

Ready-to-Use Certipur® pH Buffer solutions (4 L & 10 L) having pH values in the range of 1 to 12 are now also available in the sustainable Titripac® packaging format. This packaging ensures stability, reliability, and high-quality buffer solutions - from the first to the last drop. This hermetically sealed packaging system effectively eliminates various contamination sources, such as air, carbon dioxide, or even microorganisms during use. The outer carton can be compressed and simply disposed of together with other paper waste, and the internal liner bag can be easily folded together prior to its disposal, thereby reducing the waste volume (Figure 1).

Titripac® packaging is extremely easy-to-use. The integrated spout appears simply by pressing on the designated part of the pack. By opening the tap, the buffer solution can be withdrawn at any time – effortlessly and without the risk of contamination.

Titripac® packaging was awarded in 2016 with the Green Good Design Award due to its unique environmental benefits.

A picture of compressed Titripac® packet components ready for efficient disposal.

Figure 1.Compressed Titripac® components ready for efficient disposal.

Titripac® Packaging Advantages

  • Convenient to use – comes with integrated withdrawal tap (Figure 2)
  • Minimized packaging waste (Figure 3)
  • Reliable to the last drop: hermetically sealed packaging
  • Stability assurance even after opening (Figure 4)
  • For more detailed information on stability data for Titripac® packaging can be found in the Technical Datasheet:
    Certified Reference Materials: Ready-to- use Certipur® buffer solutions in Titripac® packaging
  • Technical datasheet now available on respective product description pages
Ready-to-Use Certipur® pH buffer solutions (4 L & 10 L)

Figure 2.Ready-to-Use Certipur® pH buffer solutions (4 L & 10 L).

Comparison of packaging waste generated by20 x 1 L solution in PE bottles and 2 x 10 L solution in Titripac® pack

Figure 3.Comparison of packaging waste generated by20 x 1 L solution in PE bottles and 2 x 10 L solution in Titripac® pack Waste of 20 x 1 L solution in PE bottles = Waste of 2 x 10 L solution in Titripac® pack.

Stability of Buffer Solutions

The stability of Ready-to-Use Certipur® pH buffer solutions in Titripac® formats was tested under daily routine conditions. Every six months, the pH value was measured with a combined glass electrode after 5-point-calibration according to DIN 19268 with reference buffer solutions according to DIN 19266, IUPAC, NIST, Ph.Eur. and USP.

The following example stability graphs (Figure 4) display the measured pH values of the pH 4.00 buffer solutions in the available Titripac® 4 L & 10 L volumes over their shelf life. See the above-mentioned Technical Datasheet for a comprehensive overview

Stability graphs of Titripac® 4 L & 10 L volume packs for storage up to 36 months for pH 4.00

Figure 4.Stability graphs for storage up to 36 months for pH 4.00.

For more information download the technical data sheet with the full stability data set.

Below are overviews on buffer solution CRMs certified at 20 °C (Table 1) and 25 °C (Table2).

Table 1.Buffer solution CRMs certified at 20 °C.
Table 2.Buffer solution CRMs certified at 25 °C.
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