Merck
CN

GRIA1

glutamate receptor, ionotropic, AMPA 1

别名:
GLUH1, GLUR1, GLURA, GluA1, HBGR1
物种:
UniProtKB ID:
基因ID:
  • Human(2890) Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14799) glutamate receptor, ionotropic, AMPA1 (alpha 1)
  • Rat(50592) glutamate receptor, ionotropic, AMPA 1
  • dog(489168) glutamate receptor, ionotropic, AMPA 1
  • domestic cat(101097621) glutamate receptor, ionotropic, AMPA 1
  • naked mole-rat(101724828) glutamate receptor, ionotropic, AMPA 1
  • domestic guinea pig(100727046) glutamate receptor, ionotropic, AMPA 1
  • sheep(443271) glutamate receptor, ionotropic, AMPA 1
  • Domestic Rabbit(100348217) glutamate receptor, ionotropic, AMPA 1
  • chicken(414893) glutamate receptor, ionotropic, AMPA 1
  • Horse(100060020) glutamate receptor, ionotropic, AMPA 1
  • cow(529618) glutamate receptor, ionotropic, AMPA 1

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Small Molecule - Agonist

货号
说明
物种
2,6-Difluoro-4-[2-(phenylsul­fonyl­amino)­ethyl­thio]­phenoxy­acet­amide, ≥98% (HPLC), solid,
物种
human
ATPA, solid,
物种
human, rat
Cyclothiazide, ,
物种
human, rat
使君子氨酸, powder,
物种
rat
N-甲基- D -天冬氨酸, ≥98% (TLC), solid,
物种
human, rat

Small Molecule - Allosteric Modulator

货号
说明
物种
CX546, ≥98% (HPLC), solid,
物种
human
吡拉西坦, ,
物种
human, rat
Cyclothiazide, ,
物种
human, rat
二氮嗪, ,
物种
rat, mouse, human
红藻氨酸 一水合物, ≥99% (TLC),
物种
human, mouse, rat

Small Molecule - Antagonist

货号
说明
物种
2,3-吡啶二甲酸, 99%,
物种
rat
2,3-二羟基喹喔啉, 98%,
物种
rat
GYKI 52466 hydrochloride, solid,
物种
human
ATPA, solid,
物种
human, rat
CNQX, ≥98% (HPLC), solid,
物种
rat

Antibodies

货号
说明
物种反应性
应用
抗谷氨酸受体1抗体, from rabbit, purified by affinity chromatography,
物种反应性
equine, horse, human, mouse, platypus, rat
应用
immunohistochemistry
immunoprecipitation (IP)

western blot
抗GluR1-NT(NT)抗体,克隆RH95, clone RH95, from mouse,
物种反应性
rat
应用
ELISA
immunocytochemistry

immunoprecipitation (IP)

western blot
抗-pan-AMPA受体(GluR1-4),克隆2D8抗体, clone 2D8, from mouse,
物种反应性
human, rat
应用
ELISA
electron microscopy

immunocytochemistry

immunofluorescence

immunohistochemistry

western blot
Anti-Glutamate Receptor 1 Antibody, phosphoSer 845, Chemicon®, from rabbit,
物种反应性
rat
应用
western blot
抗-GluR1抗体,克隆C3T,兔单克隆, culture supernatant, clone C3T, Upstate®,
物种反应性
chimpanzee, human, mouse, rat
应用
immunohistochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Blocker

货号
说明
物种
Cyclothiazide, ,
物种
human, rat
犬尿喹啉酸, ≥98%,
物种
rat, human
托吡酯, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
托吡酯, United States Pharmacopeia (USP) Reference Standard,
物种
human
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human

Small Molecule - Ligand

货号
说明
物种
使君子氨酸, powder,
物种
rat
2-溴-2-氯-1,1,1-三氟乙烷, ≥99%,
物种
human

Small Molecule - Mixed Agonist/Antagonist

货号
说明
物种
ATPA, solid,
物种
human, rat
Cyclothiazide, ,
物种
human, rat
(±)-AMPA, solid,
物种
rat
红藻氨酸 一水合物, ≥99% (TLC),
物种
human, mouse, rat
L-谷氨酸, ReagentPlus®, ≥99% (HPLC),
物种
rat, human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human GRIA1,
物种
human