Merck
CN

POLG

polymerase (DNA directed), gamma

别名:
MDP1, MIRAS, MTDPS4A, MTDPS4B, PEO, POLG1, POLGA, SANDO, SCAE
物种:
UniProtKB ID:
基因ID:
  • Human(5428) Summary: Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(18975) polymerase (DNA directed), gamma
  • Rat(85472) polymerase (DNA directed), gamma
  • Zebrafish(100150924) polymerase (DNA directed), gamma
  • Horse(100053827) polymerase (DNA directed), gamma
  • dog(488732) polymerase (DNA directed), gamma
  • naked mole-rat(101700433) polymerase (DNA directed), gamma
  • domestic cat(101083771) polymerase (DNA directed), gamma
  • cow(533090) polymerase (DNA directed), gamma
  • chicken(404292) polymerase (DNA directed), gamma
  • sheep(101123414) polymerase (DNA directed), gamma
  • domestic guinea pig(100728907) polymerase (DNA directed), gamma

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Antibodies

货号
说明
物种反应性
应用
Anti-DNA Polymerase gamma Antibody, clone 9V9D9, Rabbit Monoclonal, ,
物种反应性
human, rat
应用
western blot
Anti-POLG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-POLG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
Anti-DNA polymerase subunit gamma-1 Antibody/POLG, 1.0 mg/mL, from rabbit,
物种反应性
human
应用
immunohistochemistry
immunoprecipitation (IP)

Small Molecule - Inhibitor

货号
说明
物种
膦甲酸钠 三元 六水合物, ,
物种
rat, human

Proteins

货号
说明
物种
PrEST Antigen POLG, Prestige Antibodies® Powered by Atlas Antibodies, buffered aqueous solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Polg,
物种
mouse
MISSION® esiRNA, targeting human POLG,
物种
human