Merck
CN

VDR

vitamin D (1,25- dihydroxyvitamin D3) receptor

别名:
NR1I1
物种:
Human VDR (7421), Mouse Vdr (22337), Rat Vdr (24873), naked mole-rat Vdr (101710294), domestic guinea pig Vdr (100734655), sheep VDR (101107273), sheep VDR (100294603), cow VDR (533656), Horse VDR (100034072), domestic cat VDR (100316614) ...展开
UniProtKB ID:
P11473, B2R5Q1, G3V1V9, Q5PSV3
基因ID:
  • Human(7421) Summary: This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Feb 2011]
  • Mouse(22337) vitamin D receptor
  • Rat(24873) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • naked mole-rat(101710294) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • domestic guinea pig(100734655) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • sheep(101107273) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • sheep(100294603) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • cow(533656) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • Horse(100034072) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • domestic cat(100316614) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • dog(486588) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • chicken(395988) vitamin D (1,25- dihydroxyvitamin D3) receptor

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Small Molecule - Agonist

货号
说明
物种
PHR1237
胆钙化醇, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
C9756
胆钙化醇, ≥98% (HPLC),
物种
human
PHR1238
麦角钙化甾醇(维生素D2), Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
47763
胆钙化固醇（维生素 D3）, analytical standard,
物种
human
95220
麦角钙化醇, ≥98.0% (sum of enantiomers, HPLC),
物种
human

Small Molecule - Antagonist

货号
说明
物种
D1530
1α,25-二羟基维生素D3, ≥99% (HPLC),
物种
human
17936
1α,25-二羟基维生素D3, ≥97.0% (HPLC),
物种
human

Antibodies

货号
说明
物种反应性
应用
SAB4503071
Anti-Vitamin D Receptor antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunofluorescence
immunohistochemistry
western blot
SAB4504326
Anti-phospho-Vitamin D Receptor (pSer208) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence
western blot
HPA047740
Anti-VDR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
WH0007421M2
Monoclonal Anti-VDR antibody produced in mouse, clone 2F4, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunohistochemistry
ZRB1877
Anti-Vitamin D3 Receptor Antibody, clone 1M19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
bovine, canine, feline, human, monkey, mouse, porcine, rat
应用
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot

esiRNA

货号
说明
物种
EHU010441
MISSION® esiRNA, targeting human VDR,
物种
human