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MMP17

matrix metallopeptidase 17 (membrane-inserted)

Synonyms:
MT4-MMP
Species:
UniProtKB ID:
Gene ID:
  • Human(4326) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage. [provided by RefSeq, Jul 2008]
  • Mouse(23948) matrix metallopeptidase 17
  • Rat(288626) matrix metallopeptidase 17
  • cow(513072) matrix metallopeptidase 17 (membrane-inserted)
  • sheep(101117966) matrix metallopeptidase 17 (membrane-inserted)
  • domestic guinea pig(100718894) matrix metallopeptidase 17 (membrane-inserted)
  • naked mole-rat(101714022) matrix metallopeptidase 17 (membrane-inserted)
  • Horse(100062342) matrix metallopeptidase 17 (membrane-inserted)
  • dog(609890) matrix metallopeptidase 17 (membrane-inserted)
  • domestic cat(101098897) matrix metallopeptidase 17 (membrane-inserted)
  • chicken(416801) matrix metallopeptidase 17 (membrane-inserted)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MMP17 (Cleaved-Gln129) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
PD166793 hydrate, ≥98% (HPLC),
Species
human, rat, mouse
Marimastat, ≥98% (HPLC),
Species
human, rat, mouse

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MMP17,
Species
human
MISSION® esiRNA, targeting mouse Mmp17,
Species
mouse