CN
NR1H4
nuclear receptor subfamily 1, group H, member 4
Synonyms:
BAR, FXR, HRR-1, HRR1, RIP14
Species:
Human NR1H4 (9971), Mouse Nr1h4 (20186), Rat Nr1h4 (60351), domestic cat NR1H4 (101096997), naked mole-rat Nr1h4 (101714263), cow NR1H4 (540528), domestic guinea pig Nr1h4 (100734377), Zebrafish nr1h4 (436847), Horse NR1H4 (100052821), chicken NR1H4 (373902) ...More
UniProtKB ID:
Gene ID:
- Human(9971) Summary: This gene encodes a ligand-activated transcription factor, which shares structural features in common with nuclear hormone receptor family, such as a DNA-binding domain that targets the receptor to specific DNA sequences, and a ligand-binding domain, which interacts directly with the ligand and contains a ligand-dependent transcriptional activation domain. This protein functions as a receptor for bile acids, and when bound to bile acids, regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
- Mouse(20186) nuclear receptor subfamily 1, group H, member 4
- Rat(60351) nuclear receptor subfamily 1, group H, member 4
- domestic cat(101096997) nuclear receptor subfamily 1, group H, member 4
- naked mole-rat(101714263) nuclear receptor subfamily 1, group H, member 4
- cow(540528) nuclear receptor subfamily 1, group H, member 4
- domestic guinea pig(100734377) nuclear receptor subfamily 1, group H, member 4
- Zebrafish(436847) nuclear receptor subfamily 1, group H, member 4
- Horse(100052821) nuclear receptor subfamily 1, group H, member 4
- chicken(373902) nuclear receptor subfamily 1, group H, member 4
- dog(612928) nuclear receptor subfamily 1, group H, member 4
- sheep(101105401) nuclear receptor subfamily 1, group H, member 4
- Domestic Rabbit(100009485) nuclear receptor subfamily 1, group H, member 4
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Small Molecule - Agonist
Product Number
Description
Species
Ursodeoxycholic acid impurity standard, British Pharmacopoeia (BP) Reference Standard,
Species
human
Ursodeoxycholic acid for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-NR1H4 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-Farnesoid X Receptor/HRR1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human
Application
ELISA
western blot
western blot
Monoclonal Anti-NR1H4 antibody produced in mouse, clone 1G11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Monoclonal Anti-NR1H4, (C-terminal) antibody produced in mouse, clone 1B10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot