Merck
CN

P2RX7

purinergic receptor P2X, ligand-gated ion channel, 7

别名:
P2X7
物种:
UniProtKB ID:
基因ID:
  • Human(5027) Summary: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010]
  • Mouse(18439) purinergic receptor P2X, ligand-gated ion channel, 7
  • Rat(29665) purinergic receptor P2X, ligand-gated ion channel, 7
  • Horse(100058464) purinergic receptor P2X, ligand-gated ion channel, 7
  • domestic guinea pig(100379234) purinergic receptor P2X, ligand-gated ion channel, 7
  • chicken(771952) purinergic receptor P2X, ligand-gated ion channel, 7
  • Zebrafish(387298) purinergic receptor P2X, ligand-gated ion channel, 7
  • dog(448778) purinergic receptor P2X, ligand-gated ion channel, 7
  • domestic cat(101097922) purinergic receptor P2X, ligand-gated ion channel, 7
  • cow(286814) purinergic receptor P2X, ligand-gated ion channel, 7
  • naked mole-rat(101721795) purinergic receptor P2X, ligand-gated ion channel, 7
  • sheep(101103842) purinergic receptor P2X, ligand-gated ion channel, 7
  • Domestic Rabbit(100351535) purinergic receptor P2X, ligand-gated ion channel, 7

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Small Molecule - Antagonist

货号
说明
物种
KN-62, ≥95%, powder,
物种
human

Antibodies

货号
说明
物种反应性
应用
抗-P2RX7 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
Anti-P2RX7 antibody produced in rabbit, IgG fraction of antiserum,
物种反应性
human, mouse, rabbit
应用
immunohistochemistry
western blot
Anti-P2X7 Receptor Antibody, Chemicon®, from rabbit,
物种反应性
rat
应用
immunohistochemistry
western blot
Anti-P2RX7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-P2RX7 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human P2RX7,
物种
human