Merck
CN

PDE4C

phosphodiesterase 4C, cAMP-specific

别名:
DPDE1
物种:
Human PDE4C (5143), Mouse Pde4c (110385), Rat Pde4c (290646), dog PDE4C (609938), cow PDE4C (524624), domestic cat PDE4C (101086123), naked mole-rat Pde4c (101703048), sheep PDE4C (101111282)
UniProtKB ID:
Q08493, B3KTC4, Q9UN44, Q9UN45, Q9UN46, Q9UPJ6
基因ID:
  • Human(5143) Summary: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
  • Mouse(110385) phosphodiesterase 4C, cAMP specific
  • Rat(290646) phosphodiesterase 4C, cAMP-specific
  • dog(609938) phosphodiesterase 4C, cAMP-specific
  • cow(524624) phosphodiesterase 4C, cAMP-specific
  • domestic cat(101086123) phosphodiesterase 4C, cAMP-specific
  • naked mole-rat(101703048) phosphodiesterase 4C, cAMP-specific
  • sheep(101111282) phosphodiesterase 4C, cAMP-specific

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Small Molecule - Antagonist

货号
说明
物种
R6520
咯利普兰, solid, ≥98% (HPLC),
物种
human, mouse, rat
D9766
双嘧达莫, ≥98% (HPLC),
物种
mouse, human

Antibodies

货号
说明
物种反应性
应用
SAB1404183
Monoclonal Anti-PDE4C, (N-terminal) antibody produced in mouse, clone 4E5, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence
western blot
HPA048975
Anti-PDE4C antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
HPA054218
Anti-PDE4C antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
SAB1400197
Monoclonal Anti-PDE4C antibody produced in mouse, clone 6A10, ascites fluid,
物种反应性
human
应用
ELISA
western blot

Small Molecule - Inhibitor

货号
说明
物种
SML1099
罗氟司特, ≥98% (HPLC),
物种
human
BP571
黄酮哌酯 盐酸盐, British Pharmacopoeia (BP) Reference Standard,
物种
human
1270708
黄酮哌酯 盐酸盐, United States Pharmacopeia (USP) Reference Standard,
物种
human
Y0000736
黄酮哌酯 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物种
human
Z3003
Zardaverine, phosphodiesterase inhibitor,
物种
rat, human

Proteins

货号
说明
物种
SRP0265
PDE4C Active from mouse, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
物种
mouse
SRP0266
PDE4C1 Active human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
物种
human

esiRNA

货号
说明
物种
EMU043571
MISSION® esiRNA, targeting mouse Pde4c,
物种
mouse
EHU060201
MISSION® esiRNA, targeting human PDE4C,
物种
human