03-0184-00
SMC® Human Phospho-Tau (T181) High Sensitivity Immunoassay Kit
Used for ultrasensitive quantification of Human phospho-Tau (T181) in human serum, plasma, and cerebrospinal fluid (CSF)
Synonym(s):
pTau T181 Single Molecule Counting Kit, pTau T181 immunoassay kit, pTau T181 ultra-sensitive immunoassay, pTau Thr181 immunoassay kit
Select a Size
About This Item
Quality Level
product line
SMC®
usage
kit sufficient for 96 wells
species reactivity
human
manufacturer/tradename
SMC®
technique(s)
single molecule counting: suitable
input
serum
cerebrospinal fluid (CSF)
plasma (K2 EDTA)
UniProt accession no.
compatibility
for use with FemtoQuest™ and SMCxPRO® instruments
shipped in
wet ice
storage temp.
2-8°C
General description
Elevated levels of phospho Tau 181 in cerebrospinal fluid (CSF) serve as a biomarker for neurodegeneration, particularly in Alzheimer′s disease, where its presence correlates with disease severity and progression. Additionally, phospho Tau 181 contributes to neuroinflammation by activating glial cells, which can exacerbate neuronal damage and promote disease progression.
Application
Biochem/physiol Actions
Features and Benefits
- Ultrasensitive Detection: Enables femtogram-level measurement of pTau181 in serum, plasma or CSF.
- Enhanced Signal Resolution: Expanded dynamic range with improved signal-to-noise ratio ensures consistent and accurate assay results.
- Intuitive Assay Format: Leverages a straightforward sandwich immunoassay design for high-sensitivity detection.
- Automation-Friendly Design: Engineered for integration with automated liquid handling platforms, streamlining workflows and minimizing manual intervention.
- Specialized Scientific Support: Backed by expert teams with deep experience in SMC® assay technology.
Packaging
Analysis Note
- Sensitivity: LLOQ 940 fg/mL* (SMCxPRO® Instrument)
- Standard Curve Range: 230-240,000 fg/mL
- Intra-assay CV: <15%
- Inter-assay CV: <20%
- Linearity: Serum: 96% Plasma: 130% CSF: 138%
- Recovery: Serum: 102% Plasma: 97% CSF: 91%
Legal Information
Disclaimer
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B - STOT RE 2 Inhalation
Target Organs
Respiratory Tract
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Regulatory Information
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Related Content
通过适合的免疫检测产品，探索神经免疫和神经炎症细胞因子及神经退行性疾病生物标志物。
在强大的SMCxPRO®检测平台上，采用单分子计数(SMC®)高灵敏度免疫检测试剂盒，准确可靠地检测健康和病患来源的主要神经学蛋白分析物，进行神经科学研究。分析各种神经科学生物标志物，如神经丝蛋白轻链(NF-L)、胶质纤维酸性蛋白(GFAP)、Tau蛋白、β-淀粉样蛋白等。
Discover how to expand neuroscience biomarker research with high sensitivity immunoassays, such as Single Molecule Counting (SMC®) assays. These assays give researchers the tools they need to detect low-abundant blood-based biomarkers and expand biomarker options in neuroscience research.
Explore ultrasensitive immunoassay technology with SMC® technology, including its biomarker detection platform, advantages of high sensitivity assays, and more.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service