A1479
Angiopoietin-4 human
recombinant, expressed in NSO cells, ≥85% (SDS-PAGE), lyophilized powder
Synonym(s):
ANG-4
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About This Item
UNSPSC Code:
51111800
MDL number:
Form:
lyophilized powder
Assay:
≥85% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in NSO cells
Mol wt:
apparent mol wt 60-100 kDa by SDS-PAGE (reducing), calculated mol wt 57 kDa
biological source
human
recombinant
expressed in NSO cells
assay
≥85% (SDS-PAGE)
form
lyophilized powder
mol wt
apparent mol wt 60-100 kDa by SDS-PAGE (reducing), calculated mol wt 57 kDa
storage condition
avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)
impurities
endotoxin, tested
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... ANGPT4(51378)
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline, pH 6.8, containing 1.25 mg bovine serum albumin.
Analysis Note
The biological activity is measured by its ability to compete with biotinylated recombinant human ANG-2 for binding to immobilized Tie-2/Fc in an ELISA.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
常规特殊物品
胰岛素激素类产品
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Spencer B Mamer et al.
Scientific reports, 7(1), 16439-16439 (2017-11-29)
Nearly all studies of angiogenesis have focused on uni-family ligand-receptor binding, e.g., VEGFs bind to VEGF receptors, PDGFs bind to PDGF receptors, etc. The discovery of VEGF-PDGFRs binding challenges this paradigm and calls for investigation of other ligand-receptor binding possibilities.
M Nishimura et al.
FEBS letters, 448(2-3), 254-256 (1999-04-28)
A cDNA clone encoding angiopoietin-3 protein (Ang3), a novel member of the angiopoietin family, was identified. Ang3 cDNA was cloned from a human aorta cDNA library. Ang3 is a 503 amino acid protein having 45.1% and 44.7% identity with human
D M Valenzuela et al.
Proceedings of the National Academy of Sciences of the United States of America, 96(5), 1904-1909 (1999-03-03)
The angiopoietins have recently joined the members of the vascular endothelial growth factor family as the only known growth factors largely specific for vascular endothelium. The angiopoietins include a naturally occurring agonist, angiopoietin-1, as well as a naturally occurring antagonist
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