类型
Type XIV
表单
solid
颜色
white
溶解性
water: 2 mg/mL, clear to hazy, colorless
储存温度
2-8°C
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一般描述
来自鲱鱼睾丸的脱氧核糖核酸钠盐，也称为HtDNA，是DNA结合剂研究的天然DNA来源。 HtDNA的检出限约为5.0ng，光散射强度（I(LS)）的线性范围为0.05 ~ 2.5 mµg。
应用
从鲱鱼睾丸中提取的脱氧核糖核酸钠盐被用于研究调节DNA结构和功能的DNA结合剂。鲱鱼睾丸DNA也用于溶液中DNA行为的物理化学研究。
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
低风险生物材料
此项目有
Assaf Marcus et al.
Immunity, 49(4), 754-763 (2018-10-18)
Detection of cytosolic DNA by the enzyme cGAS triggers the production of cGAMP, a second messenger that binds and activates the adaptor protein STING, which leads to interferon (IFN) production. Here, we found that in vivo natural killer (NK) cell killing
X Du et al.
Talanta, 55(1), 93-98 (2008-10-31)
The interaction of histone with nucleic acids was characterized by light-scattering measurement using a common spectrofluorometer. Thereby, a sensitive and convenient method for the determination of nucleic acids was established. At pH 4.5-6.5, the interaction of histone with nucleic acids
Larisa I Labzin et al.
The EMBO journal, 38(21), e101365-e101365 (2019-08-31)
Inflammasomes are potent innate immune signalling complexes that couple cytokine release with pro-inflammatory cell death. However, pathogens have evolved strategies to evade this cell autonomous system. Here, we show how antibodies combine with innate sensors in primary human macrophages to
Renée M Van der Sluis et al.
PLoS pathogens, 16(2), e1008151-e1008151 (2020-02-29)
HIV latency is the major barrier to a cure for people living with HIV (PLWH) on antiretroviral therapy (ART) because the virus persists in long-lived non-proliferating and proliferating latently infected CD4+ T cells. Latently infected CD4+ T cells do not
Gillian Dunphy et al.
Molecular cell, 71(5), 745-760 (2018-09-08)
DNA damage can be sensed as a danger-associated molecular pattern by the innate immune system. Here we find that keratinocytes and other human cells mount an innate immune response within hours of etoposide-induced DNA damage, which involves the DNA sensing
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