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Merck
CN

EDEGLY

酶蛋白去糖基化试剂盒

别名:

Glycosylation Release Kit

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关于此项目

NACRES:
NA.32
UNSPSC Code:
12352202
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conjugate

(N-linked)
(O-linked)

shipped in

wet ice

storage temp.

2-8°C

Quality Level

Application

酶促蛋白去糖基化试剂盒用于:
  • 蛋白质去糖基化
  • 组织因子途径抑制因子(TFPI)去糖基化α以及β
  • 天然exo-β-(1,3)-葡聚糖酶EXG1的去糖基化

酶解蛋白去糖基化试剂盒已用于各种酶的去糖基化。

Features and Benefits

酶蛋白去糖基化试剂盒具有以下特点:
  • 适用于两mg以上规模的糖蛋白去糖基化
  • 中性pH值下单步反应
  • 天然&变性过程
  • 蛋白质无降解
  • 去除含聚唾液酸的O连接糖
  • 随附对照糖蛋白

General description

酶蛋白去糖基化试剂盒包含从糖蛋白中完整去除N连接和单一O连接碳水化合物所需的所有酶和试剂。该试剂盒用于裂解Core 2 O连接碳水化合物复合物,包括含有聚乳糖胺的碳水化合物。

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Repr. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1

存储类别

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

监管及禁止进口产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Angela Mika et al.
PLoS neglected tropical diseases, 5(9), e1331-e1331 (2011-10-08)
Pruritic scabies lesions caused by Sarcoptes scabiei burrowing in the stratum corneum of human skin facilitate opportunistic bacterial infections. Emerging resistance to current therapeutics emphasizes the need to identify novel targets for protective intervention. We have characterized several protein families
Roman Szabo et al.
PloS one, 13(4), e0194660-e0194660 (2018-04-05)
Prostasin (CAP1/PRSS8) is a glycosylphosphatidylinositol (GPI)-anchored serine protease that is essential for epithelial development and overall survival in mice. Prostasin is regulated primarily by the transmembrane serine protease inhibitor, hepatocyte growth factor activator inhibitor (HAI)-2, and loss of HAI-2 function
Jonathan Trapala et al.
Protein expression and purification, 176, 105718-105718 (2020-08-11)
Exo-inulinases are versatile enzymes that have gained attention in recent years due to their ability to hydrolyze linear and branched polyfructose chains found in inulines. Agavin, a branched inulin, is found in Agave plant, the raw matter to produce tequila.
Noémie Caillot et al.
The Journal of allergy and clinical immunology, 140(3), 759-770 (2016-12-15)
Eligibility to immunotherapy is based on the determination of IgE reactivity to a specific allergen by means of skin prick or in vitro testing. Biomarkers predicting the likelihood of clinical improvement during immunotherapy would significantly improve patient selection. Proteins were differentially
Guillain-Barre syndrome: First description of a snake envenomation aetiology
Neil J, et al.
Journal of Neuroimmunology, 242(1-2), 72-77 (2012)

商品

Information about Glycoprotein deglycosylation. The diversity of oligosaccharide structures, both O-linked and N-linked, often results in heterogeneity in the mass and charge of glycoproteins.

Explore strategies for releasing N-linked glycans with PNGase F, PNGase A & native & sequential deglycosylation with endoglycosidases & exoglycosidases.

Protein modifications are crucial for disease study. Analysis methods are key.

Find deglycosylation kits for your research. Review the different features of deglycosylation kits for glycoproteins, enzymatic proteins, and native proteins.

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