biological source
Monkey (Cynomolgus spp.)
form
liquid
specific activity
≥5000 units/mg protein
packaging
vial of ~10 mg
shipped in
dry ice
storage temp.
−70°C
Application
Microsomes from Liver, Pooled has been used to measure the in vitro stabilities of the prodrugs. It has also been used in microsomal incubation to generate BTX-3 metabolites to serve as references for liquid chromatography with tandem mass spectrometry (LC-MS/MS) analyses of urine.
Biochem/physiol Actions
Microsomal cytochrome P450 proteins can catalyze the transfer of a single oxygen atom to endogenous and exogenous compounds, like steroids and phenobarbital, meant for excretion and detoxification.
肝微粒体是来源于肝细胞内质网的亚细胞颗粒。这些微粒体是药物代谢酶（包括细胞色素 P-450）的丰富来源。不同来源的微粒体池有助于研究外源代谢和药物相互作用。
药物代谢酶的来源，包括细胞色素 P-450。
Other Notes
One unit will produce 1.0 picomole of 6 beta-hydroxytestosterone per minute at pH 7.4 at 37 deg C.
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wgk
WGK 3
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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相关内容
Datasheet
Biochemistry and cell biology
The Cytokine Handbook (2016)
Ann Abraham et al.
Toxicon : official journal of the International Society on Toxinology, 52(2), 237-245 (2008-06-28)
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Kumar Sachin Singh et al.
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Isoprenoids are vital for all organisms, in which they maintain membrane stability and support core functions such as respiration1. IspH, an enzyme in the methyl erythritol phosphate pathway of isoprenoid synthesis, is essential for Gram-negative bacteria, mycobacteria and apicomplexans2,3. Its
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